Padres vs. Astros Odds & Betting Predictions - April 19, 2025

Padres at Astros

12:10 am • SCHN
4 - 6
Starting Pitchers
pitcherteameraw-l
Ryan Gusto logoR.GustoHouston Astros logo3.182-1
Kyle Hart logoK.HartSan Diego Padres logo6.482-1

Padres at Astros Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Padres
15-5
+1.5
+1.5-152
o9-112
+140
Astros
9-10
u9
-1.5+126
u9-112
-173
location pinSaturday 12:10 a.m.
April 19, 2025
Daikin ParkHouston
Padres vs. Astros Expert Picks
Top Shelf Action 🥃
Top Shelf Action 🥃
Last 30d: 376-522-15 (+19.0u)
R.Gusto u15.5 Outs-175
1.14u
4.58% ev
YBK Picks.com
Last 30d: 53-56-2 (-12.3u)
HOU -1-115
1.74u
Top Shelf Action 🥃
Top Shelf Action 🥃
Last 30d: 376-522-15 (+19.0u)
C.Walker o0.5 HR+440
0.2u
C.Walker o0.5 HR+420
0.2u
3.27% ev
Sir Lockselot
Sir Lockselot
Last 30d: 28-73-0 (-54.8u)
F.Tatis o0.5 RBI+130
2u
🔑 Fernando Tatis 1+ RBI +130 (DraftKings) 2u Nando is locked in this season. 14 RBI in in 18 GP. 2 mid pitchers going so I expect a lot of runs (so does Vegas with a 9.5 O/U. BetAlytics model loves this one too. 5 ⭐️ grade and a 52.8% expected win probability Code LOCKSELOT for 25% off at BetAlytics Join 👉🔗 https://www.betalytics.com/
Steak Friend
Steak Friend
Last 30d: 196-205-5 (+5.8u)
HOU -152
1u
Top Shelf Action 🥃
Top Shelf Action 🥃
Last 30d: 376-522-15 (+19.0u)
R.Gusto u4.5 Ks-155
0.84u
3.41% ev
Boomer Betz
Boomer Betz
Last 30d: 136-146-5 (+21.8u)
K.Hart u3.5 Ks-106
0.94u
#SO
Mjaybrod
Mjaybrod
Last 30d: 85-83-3 (-1.6u)
HOU -137
0.73u
Bring out the garbage cans
Anders
Anders
Last 30d: 6-6-1 (+0.2u)
HOU -1.5+155
1.55u
Love the price and fits my favorite MLB system
Sean Zerillo
Sean Zerillo
Last 30d: 167-176-19 (-1.3u)
HOU -125 (F5)
0.25u
Bet to -140
Picks  Office
Picks Office
Last 30d: 93-70-3 (+19.5u)
HOU -125
0.8u
Astros are undervalued here — Ryan Gusto owns a 3.00 ERA, 2.83 xERA, and elite 31.9% K rate. Hart? 5.40 ERA, just 17.4% Ks. Gusto’s walk rate just 6.4%, limits damage. Plus run values on all pitch types. Hard contact allowed under 45% — dude’s dialed in. Houston lineup’s stacked — six starters with xwOBA north of .300, setting tone early. Yordan (.398) + Peña (.393) lead the charge. Average exit velocity above 90 mph, launch angle dialed for damage. Home park helps slug — Minute Maid boosts their profile notably. Astros thrive at home — offense up 15%, best RISP avg in MLB this season.
Sean Zerillo
Sean Zerillo
Last 30d: 167-176-19 (-1.3u)
Under 9-115
0.58u
Friday. Assuming roof closed. Bet to -115
HOU -120
0.42u
Friday. Flat to -130

Padres vs. Astros Previews & Analysis

  • Juicy Strikeout Prop Edges Today article feature image

    Juicy Strikeout Prop Edges Today

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    Apr 18, 2025 UTC
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Prop Odds Comparison

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Padres vs. Astros Public Betting Percentages

Away Logo

Padres

Public

59%

Bets%

41%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Astros
9-104-65-45-74-2
Padres
14-612-12-59-35-3

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Astros
8-9-25-53-4-26-61-3-2
Padres
9-10-14-8-15-25-6-14-4

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Astros
9-105-54-56-63-3
Padres
15-512-13-411-14-4

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Apr 16th@STLL 1-4-1.5 LU 8.5STL -111
Apr 15th@STLW 2-0-1.5 WU 7.5HOU -134
Apr 14th@STLL 3-8-1.5 LO 7STL -110
Apr 13thLAAW 7-3-1.5 WO 8.5HOU -165
Apr 12thLAAL 1-4-1.5 LU 9LAA -164

Astros vs. Padres Injury Updates

Astros Injuries

  • Lance McCullers
    P

    McCullers is out with arm

    Out

  • Taylor Trammell
    OF

    Trammell is out with calf

    Out

  • Cristian Javier
    P

    Javier is out with elbow

    Out

  • Luis Garcia
    P

    Garcia is out with elbow

    Out

  • Pedro Leon
    OF

    Leon is out with knee

    Out

  • J.P. France
    P

    France is out with shoulder

    Out

  • Spencer Arrighetti
    P

    Arrighetti is out with thumb

    Out

Padres Injuries

  • Joe Musgrove
    P

    Musgrove is out for season with elbow

    Out for Season

  • Yu Darvish
    P

    Darvish is out with elbow

    Out

  • Jason Heyward
    OF

    Jason Heyward has been scratched Friday.

    Out

  • Matt Waldron
    P

    Waldron is out with hamstring

    Out

  • Jackson Merrill
    OF

    Merrill is out with hamstring

    Out

Padres vs. Astros Box Score
Padres Player Stats
Projected
PITCHERPCIPKER
Kyle Hart logoLK.Hart, P79525
Alek Jacob logoRA.Jacob, P20210
Yuki Matsui logoLY.Matsui, P20111
HITTERSH-ABRHRRBI
Fernando Tatis logo1F.Tatis, RF1-4100
Luis Arraez logo2L.Arraez, 1B3-5112
Manny Machado logo3M.Machado, 3B0-4000
Xander Bogaerts logo4X.Bogaerts, SS1-4100
Gavin Sheets logo5G.Sheets, DH2-4100
Oscar Gonzalez logo6O.Gonzalez, LF2-4001
Jose Iglesias logo7J.Iglesias, 2B2-4000
Tyler Wade logo8T.Wade, CF1-4001
Martin Maldonado logo9M.Maldonado, C0-3000
Connor Joe logo9C.Joe, PH0-1000
Astros Player Stats
Projected
PITCHERPCIPKER
Ryan Gusto logoRR.Gusto, P68522
Steven Okert logoLS.Okert, P14120
Bryan King logoLB.King, P16102
Bryan Abreu logoRB.Abreu, P15120
Josh Hader logoLJ.Hader, P10110
HITTERSH-ABRHRRBI
Jose Altuve logo1J.Altuve, LF2-4000
Isaac Paredes logo2I.Paredes, 3B0-4000
Yordan Alvarez logo3Y.Alvarez, DH0-4000
Christian Walker logo4C.Walker, 1B1-4100
Jeremy Pena logo5J.Pena, SS1-3100
Yainer Diaz logo6Y.Diaz, C2-4101
Brendan Rodgers logo7B.Rodgers, 2B1-4000
Jake Meyers logo8J.Meyers, CF3-4101
Cam Smith logo9C.Smith, RF2-4224
Chas McCormick logo9C.McCormick, RF0-0000

Padres vs. Astros Odds Comparison

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Padres at Astros Team Totals

MatchupOverUnder
Padres
15-5
N/A
N/A
Astros
9-10
N/A
N/A