Reds vs. Cardinals Odds & Betting Predictions - September 17, 2025

Reds at Cardinals

5:15 pm • FDSMW

Cincinnati Reds

35-38

6 - 2

St. Louis Cardinals

40-33

pitcher		team	era	w-l
A.Pallante			5.31	6-15
B.Singer			4.03	14-12

MatchupOpenSpreadTotalMoneyline
Reds 35-38	-1.5	-1.5+138	o8.5-105	-120
Cardinals 40-33	u8.5	+1.5-165	u8.5-115	+102

Wednesday 5:15 p.m.

September 17, 2025

Busch StadiumSt. Louis

Under 8.5-113

CIN -120

B.Singer o16.5 Outs-130

Singer has posted 6 straight quality starts. After stumbling in his first game out of the All-Star break, he's put together a dominant 9-start stretch with a 2.21 ERA and ERA estimators in the mid-3.00s. Singer has gone 6+ innings in all but one start over that span. St. Louis ranks 27th or worse in OPS, wOBA, and wRC+ vs. RHP over the past 30 days. They're right at league average in terms of pitches seen per plate appearance. It's a solid matchup.

CIN -0.5 (F5)+115

1.15u

A.Pallante u5.5 Hits Allowed+104

0.48u

Under 8.5-110

Under 8.5-105

0.5u

Bet to 8 (+100)

Reds vs Cardinals: Over/Under Pick for Wednesday Afternoon
Action Network Staff•
Sep 17, 2025 UTC

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MLB Public Betting

Cardinals are 2-3 in their last 5 games.
Cardinals are 1-4 in their last 5 games against the spread
Cardinals are 22-13 in their road games against the spread
The totals have gone OVER in 1 of Cardinals' last 5 games
The totals have gone OVER in 17 of Cardinals' 38 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Cardinals	44-29	22-16	22-13	9-6	35-22
Reds	39-34	18-20	21-14	13-11	26-23

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Cardinals	31-38-4	17-19-2	14-19-2	5-9-1	25-29-3
Reds	44-28-1	23-15	21-13-1	15-9	29-19-1

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Cardinals	40-33	21-17	19-16	11-4	29-28
Reds	35-38	19-19	16-19	14-10	21-28

date	opponent	score	spread	over/under	moneyline
Sep 16th	CIN	W 3-0	+1.5 W	U 8	STL +105
Sep 15th	CIN	L 6-11	+1.5 L	O 8.5	CIN -113
Sep 14th	@MIL	W 3-2	+1.5 W	U 8.5	STL +160
Sep 14th	@MIL	L 8-9	+1.5 W	O 8	MIL +154
Sep 13th	@MIL	L 2-8	+1.5 L	O 8.5	MIL +158

Hunter Greene
SP
Greene is out with elbow
Out

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PITCHER	PC	IP	K	ER
RB.Singer, P	97	5.2	6	1
RG.Ashcraft, P	5	0.1	1	0
RC.Burns, P	26	2	1	0
RE.Pagan, P	22	1	3	0

HITTERS	H-AB	R	HR	RBI
1G.Lux, DH	3-5	1	0	0
2N.Marte, RF	2-5	0	0	0
3W.Benson, CF	0-5	0	0	0
4A.Hays, LF	1-5	1	0	0
5S.Stewart, 3B	1-2	1	0	0
5S.Espinal, PR	0-1	1	0	0
5S.Espinal, 3B	0-1	1	0	0
6E.De La Cruz, SS	0-3	1	0	0
7S.Steer, 1B	3-4	1	1	5
8J.Trevino, C	1-4	0	0	0
9M.McLain, 2B	0-4	0	0	0

PITCHER	PC	IP	K	ER
RA.Pallante, P	102	5	3	4
RJ.Alcala, P	22	1	1	0
RM.Svanson, P	19	1	2	2
RR.Fernandez, P	11	1	2	0
RG.Graceffo, P	16	1	1	0

HITTERS	H-AB	R	HR	RBI
1L.Nootbaar, LF	1-3	1	0	0
2I.Herrera, DH	0-4	0	0	0
3A.Burleson, 1B	2-3	1	1	1
4N.Arenado, 3B	0-4	0	0	0
5N.Gorman, 2B	0-4	0	0	0
6T.Saggese, SS	1-3	0	0	0
7J.Crooks, C	1-4	0	0	0
8J.Walker, RF	0-4	0	0	0
9V.Scott, CF	0-2	0	0	0