Reds vs. Cardinals Odds & Betting Predictions - September 17, 2025

Reds at Cardinals

5:15 pm • FDSMW

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Cincinnati Reds

75-76

St. Louis Cardinals

74-78

pitcher		team	era	w-l
A.Pallante			5.23	6-14
B.Singer			3.94	13-10

MatchupOpenSpreadTotalMoneyline
Reds 75-76	-1.5	-1.5+135	o8.5-105	-120
Cardinals 74-78	u8.5	+1.5-165	u8.5-115	+102

Wednesday 5:15 p.m.

September 17, 2025

Busch StadiumSt. Louis

84°Fahrenheit

0%Rain

2Wind

Under 8.5-113

1.13u

CIN -120

1.2u

B.Singer o16.5 Outs-130

1.3u

Singer has posted 6 straight quality starts. After stumbling in his first game out of the All-Star break, he's put together a dominant 9-start stretch with a 2.21 ERA and ERA estimators in the mid-3.00s. Singer has gone 6+ innings in all but one start over that span. St. Louis ranks 27th or worse in OPS, wOBA, and wRC+ vs. RHP over the past 30 days. They're right at league average in terms of pitches seen per plate appearance. It's a solid matchup.

CIN -0.5 (F5)+115

Under 8.5-110

1.1u

Under 8.5-110

1.1u

Under 8.5-105

1.05u

Under 8.5-105

0.53u

Bet to 8 (+100)

Reds vs Cardinals: Over/Under Pick for Wednesday Afternoon
Action Network Staff•
Sep 17, 2025 UTC

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No props found

MLB Public Betting

Cardinals are 2-3 in their last 5 games.
Cardinals are 3-2 in their last 5 games against the spread
Cardinals are 37-38 in their road games against the spread
The totals have gone OVER in 3 of Cardinals' last 5 games
The totals have gone OVER in 38 of Cardinals' 77 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Cardinals	75-77	38-39	37-38	25-41	49-36
Reds	77-72	38-34	39-38	27-38	50-33

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Cardinals	76-69-7	38-36-3	38-33-4	33-28-5	42-41-2
Reds	56-84-9	25-41-6	31-43-3	20-42-3	35-42-6

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Cardinals	74-78	42-35	32-43	33-33	40-45
Reds	75-76	39-33	35-42	34-31	40-43

date	opponent	score	spread	over/under	moneyline
Sep 16th	CIN	W 3-0	+1.5 W	U 8	STL +105
Sep 15th	CIN	L 6-11	+1.5 L	O 8.5	CIN -113
Sep 14th	@MIL	W 3-2	+1.5 W	U 8.5	STL +160
Sep 14th	@MIL	L 8-9	+1.5 W	O 8	MIL +154
Sep 13th	@MIL	L 2-8	+1.5 L	O 8.5	MIL +158

Masyn Winn
SS
Masyn Winn (knee) has been scratched Friday.
Out

Noelvi Marte
3B
Marte is day-to-day with side
Day-to-Day
Reiver Sanmartin
RP
Sanmartin is out with elbow
Out
Brandon Williamson
SP
Williamson is out for season with elbow
Out for Season
Graham Ashcraft
RP
Ashcraft is out with groin
Out
Chase Burns
SP
Burns is out with hip
Out
Julian Aguiar
SP
Aguiar is out for season with elbow
Out for Season
Rhett Lowder
SP
Lowder is out with elbow
Out
Carson Spiers
RP
Spiers is out with shoulder
Out

See more MLB Injuries

PITCHER		W-L	ERA	WHIP	K/9
RB.Singer, P		13-10	3.94	1.236	8.63

HITTERS	AVG	OBP	SLG	HR
1G.Lux, DH	.263	.349	.369	5
2N.Marte, RF	.272	.313	.473	13
3W.Benson, CF	.233	.281	.461	12
4A.Hays, LF	.266	.318	.459	15
5S.Stewart, 3B	.275	.293	.575	4
6E.De La Cruz, SS	.264	.334	.435	19
7S.Steer, 1B	.237	.308	.396	17
8J.Trevino, C	.249	.285	.370	4
9M.McLain, 2B	.225	.306	.349	14

PITCHER		W-L	ERA	WHIP	K/9
RA.Pallante, P		6-14	5.23	1.426	6.04

HITTERS	AVG	OBP	SLG	HR
1L.Nootbaar, LF	.236	.322	.369	13
2I.Herrera, DH	.283	.370	.456	16
3A.Burleson, 1B	.283	.335	.451	17
4N.Arenado, 3B	.236	.294	.367	10
5N.Gorman, 2B	.210	.304	.384	14
6T.Saggese, SS	.263	.302	.347	2
7J.Crooks, C	.083	.120	.208	1
8J.Walker, RF	.215	.272	.303	5
9V.Scott, CF	.217	.304	.299	5