Reds vs. Cubs Odds & Betting Predictions - May 6, 2026

Reds at Cubs

11:40 pm • MARQ
6 - 7
Starting Pitchers
pitcherteameraw-l
Colin Rea logoC.ReaChicago Cubs logo4.867-7
Brady Singer logoB.SingerCincinnati Reds logo4.535-9

Reds at Cubs Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Reds
49-55
+1.5
+1.5-150
o8-118
+145
Cubs
59-46
u8.5
-1.5+125
u8-104
-172
location pinWednesday 11:40 p.m.
May 06, 2026
Wrigley FieldChicago
Reds vs. Cubs Expert Picks
Sean Koerner🔮
Sean Koerner🔮
Last 30d: 29-41-1 (-2.8u)
C.Rea u4.5 Ks+107
0.5u
Scott Rickenbach
Scott Rickenbach
Last 30d: 65-59-2 (-1.9u)
Under 8.5-111
1u
Frank Ammirante
Frank Ammirante
Last 30d: 323-378-8 (-55.1u)
Under 0.5 (1st Inn)-130
1.3u
RoyalsProps
RoyalsProps
Last 30d: 0-0-0 (+0.0u)
S.Suzuki o1.5 Hits + Runs + RBIs-122
1u
Brandon Kravitz
Brandon Kravitz
Last 30d: 45-42-0 (+6.1u)
Under 8-105
1.05u
Matt Trollo
Matt Trollo
Last 30d: 79-89-2 (-9.2u)
CHC -168
0.6u
(FD) This is mostly a bet against Singer, who has been awful (4.84 SIERA/6.18 xERA). Rea has bee more than a run better (3.57/4.43). I also give the Cubs a near 30 point wRC+ edge (127/116 Hm/v RHP vs 79/91 – proj. LU 121 vs 97 vs RHP since LY). Proj. defense 19 FRV edge for CHC and bullpen estimators full run better. I have full game and F5 rated evenly. Flip a coin. Split it. (Good to -180)
Doug Ziefel
Doug Ziefel
Last 30d: 96-100-1 (+6.7u)
Under 8.5-125
0.63u

Reds vs. Cubs Previews & Analysis

  • Reds vs Cubs: PRO's Top Prop Edge for Wednesday article feature image

    Reds vs Cubs: PRO's Top Prop Edge for Wednesday

    Action Network Staff
    May 6, 2026 UTC
  • 60% Weather System + Strikeout Angle article feature image

    60% Weather System + Strikeout Angle

    Action AI
    May 6, 2026 UTC
  • Wednesday's Wrigley Field Wind Report for Cubs-Reds article feature image

    Wednesday's Wrigley Field Wind Report for Cubs-Reds

    Tanner McGrath
    May 6, 2026 UTC
See more MLB Coverage Right Arrow

Prop Odds Comparison

Right Arrow
Right Arrow

No props found

Line Movement Tracker

Right Arrow
Right Arrow

Reds vs. Cubs Public Betting Percentages

Away Logo

Reds

Public

14%

Bets%

86%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Cubs
47-5820-3227-2629-4118-16
Reds
56-4824-2632-2216-1540-32

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Cubs
56-4928-2428-2536-3420-14
Reds
56-47-127-2329-24-120-1136-35-1

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Cubs
59-4630-2229-2440-3018-16
Reds
49-5522-2827-2717-1432-40

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
May 5thCINW 3-2-1.5 LU 8CHC -165
May 4thCINW 5-4-1.5 LU 11.5CHC -219
May 3rdARIW 8-4-1.5 WO 11.5CHC -157
May 2ndARIW 2-0-1.5 WU 7CHC -170
May 1stARIW 6-5-1.5 LO 7CHC -149

Reds vs. Cubs Injury Updates

Reds Injuries

    Cubs Injuries

    • Tyler Austin
      IF

      Austin is out with knee

      Out

    • Justin Steele
      P

      Steele is out with elbow

      Out

    Reds vs. Cubs Box Score
    Reds Player Stats
    Projected
    PITCHERPCIPKER
    Brady Singer logoRB.Singer, P96664
    Sam Moll logoLS.Moll, P110.200
    Pierce Johnson logoRP.Johnson, P50.100
    Tejay Antone logoRT.Antone, P12120
    Graham Ashcraft logoRG.Ashcraft, P27112
    Brock Burke logoLB.Burke, P110.210
    HITTERSH-ABRHRRBI
    TJ Friedl logo1T.Friedl, CF1-3100
    Dane Myers logo1D.Myers, PH0-1000
    Dane Myers logo1D.Myers, CF0-1000
    JJ Bleday logo2J.Bleday, LF2-5001
    Elly De La Cruz logo3E.De La Cruz, SS0-4003
    Sal Stewart logo4S.Stewart, 3B0-4000
    Ke'Bryan Hayes logo4K.Hayes, 3B0-0000
    Nathaniel Lowe logo5N.Lowe, DH1-4000
    Blake Dunn logo5B.Dunn, PR0-0000
    Blake Dunn logo5B.Dunn, DH0-0000
    Spencer Steer logo6S.Steer, 1B1-5111
    Will Benson logo7W.Benson, RF2-4100
    Jose Trevino logo8J.Trevino, C0-3000
    Tyler Stephenson logo8T.Stephenson, PH1-1100
    Tyler Stephenson logo8T.Stephenson, C1-1100
    Matt McLain logo9M.McLain, 2B2-3211
    Cubs Player Stats
    Projected
    PITCHERPCIPKER
    Colin Rea logoRC.Rea, P985.151
    Jacob Webb logoRJ.Webb, P141.210
    Phil Maton logoRP.Maton, P12110
    Corbin Martin logoRC.Martin, P11003
    Hoby Milner logoLH.Milner, P25111
    Trent Thornton logoRT.Thornton, P6100
    HITTERSH-ABRHRRBI
    Nico Hoerner logo1N.Hoerner, 2B0-5100
    Moises Ballesteros logo2M.Ballesteros, DH0-3000
    Matt Shaw logo2M.Shaw, PH0-0000
    Michael Conforto logo2M.Conforto, PH0-1000
    Michael Conforto logo2M.Conforto, DH0-1000
    Miguel Amaya logo2M.Amaya, PH0-0000
    Alex Bregman logo3A.Bregman, 3B1-4100
    Ian Happ logo4I.Happ, LF3-5212
    Seiya Suzuki logo5S.Suzuki, RF1-4101
    Michael Busch logo6M.Busch, 1B1-3001
    Carson Kelly logo7C.Kelly, C1-4100
    Pete Crow-Armstrong logo8P.Crow-Armstrong, CF2-3112
    Dansby Swanson logo9D.Swanson, SS1-4000

    Reds vs. Cubs Odds Comparison

    Right Arrow

    Could not load odds

    Reds at Cubs Team Totals

    MatchupOverUnder
    Reds
    49-55
    N/A
    N/A
    Cubs
    59-46
    N/A
    N/A