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Marlins vs Rockies Prediction, Pick, Odds for Wednesday, September 17

Marlins vs Rockies Prediction, Pick, Odds for Wednesday, September 17 article feature image
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Photo by Ron Chenoy-Imagn Images. Pictured: Hunter Goodman

The Colorado Rockies host the Miami Marlins on September 17, 2025. First pitch from Coors Field is scheduled for 8:40 p.m. EDT; the game will be broadcast on COLR.

The Marlins took the opener of this three-game series yesterday, defeating the Rockies 6-5.

Find my MLB betting preview and Marlins vs Rockies prediction below, as well as probable pitchers, betting trends, injury reports and more.

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My Marlins vs Rockies Prediction

  • Marlins vs Rockies pick: Over 10.5 (-110)

My Marlins vs Rockies best bet is Over 10.5 total runs in this game. Make sure to find the best odds by checking our live MLB odds page.


Marlins vs Rockies Odds

Marlins Logo
Wednesday, Sep 17
8:40 p.m. ET
COLR
Rockies Logo
Marlins Odds
SpreadTotalMoneyline
-1.5
-105
10.5
-110o / -110u
-160
Rockies Odds
SpreadTotalMoneyline
+1.5
-115
10.5
-110o / -110u
+135
Odds via bet365. Get up-to-the-minute MLB odds here.
bet365 Logo

Marlins vs Rockies Projected Starting Pitchers

LHP Ryan Weathers (MIA)StatRHP McCade Brown (COL)
2-1W-L0-4
0.4fWAR (FanGraphs)-0.2
2.73 / 3.04ERA / xERA9.88 / 7.07
3.99 / 3.95FIP / xFIP7.39 / 6.79
1.04WHIP2.12
15.7K-BB%1.4
45.2GB%38.0
107Stuff+96
103Location+89

Marlins vs Rockies Preview

The first game of this series totaled 11 runs, and tonight's starter for the Rockies is McCade Brown, who has been hammered this season.

Brown has never reached the fifth inning in four starts so far in 2025. In his last outing at home, he gave up six earned runs in just one and 2/3 innings.

Coors Field, of course, is a huge factor since it offers the best hitting conditions of any major league stadium. Even the Rockies, who have the worst offense among all 30 teams, manage to raise their wRC+ rating from 75 overall to 85 at Coors.

The Marlins have the 21st-ranked offense in wRC+ but improve to 15th against right-handers like Brown.

Additionally, Colorado's bullpen is next-to-last in ERA with 5.27, while the Marlins are 21st with 4.35.

This aligns with our Bet Labs recommendation for the over in this game.

This system targets games played at Coors Field, known for its high-scoring potential due to its altitude.

The focus is on games in August, September, and October, when late-season dynamics can influence outcomes. The closing total for the game must be between 0 and 11.

This strategy takes the over as the recommended approach, leveraging the tendency for higher run outputs at Coors Field during these months.

Pick: Over 10.5 (-110, bet365)


Marlins vs Rockies Betting Trends


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