76ers vs. Celtics Odds & Betting Predictions - October 22, 2025

76ers at Celtics

11:30 pm • NBCS-BOS

Philadelphia 76ers

@

Boston Celtics

MatchupOpenSpreadTotalMoneyline
76ers 1-3	+1.5	+2.5-110	o226.5-112	+118
Celtics 3-1	u222.5	-2.5-110	u226.5-108	-142

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Wednesday 11:30 p.m.

October 22, 2025

TD GardenBoston

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NBA Public Betting

Celtics are 4-1 in their last 5 games.
Celtics are 2-3 in their last 5 games against the spread
Celtics are 20-18 in their road games against the spread
The totals have gone OVER in 2 of Celtics' last 5 games
The totals have gone OVER in 21 of Celtics' 41 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Celtics	38-41-3	18-23	20-18-3	37-39-3	1-2
76ers	27-53-2	12-28-1	15-25-1	8-19	19-34-2

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Celtics	37-45	21-20	16-25	37-42	0-3
76ers	47-33-2	21-19-1	26-14-1	15-10-2	32-23

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Celtics	61-21	N/A	N/A	60-19	1-2
76ers	24-58	N/A	N/A	15-12	9-46

date	opponent	score	spread	over/under	moneyline
Oct 15th	TOR	W 110-108	-5 L	U 232	BOS -170
Oct 12th	CLE	W 138-107	-7.5 W	O 231.5	BOS -285
Oct 10th	@TOR	L 105-107	-2.5 L	U 229	TOR -148
Oct 9th	@MEM	W 121-103	-4 W	U 232	BOS -160
Jul 20th	ATL	W 101-80	+1 W	U 185.5	BOS -105

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MatchupOverUnder
76ers 1-3	N/A	N/A
Celtics 3-1	N/A	N/A