Duke vs. Notre Dame Odds & Betting Predictions - February 25, 2026

Duke at Notre Dame

12:00 am • ESPN
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Duke at Notre Dame Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Duke
25-2
-14.5
-17.5-110
o140.5-110
-2642
Notre Dame
12-15
u139
+17.5-110
u140.5-110
+1202
location pinWednesday 12:00 a.m.
February 25, 2026
Purcell PavilionSouth Bend
Duke vs. Notre Dame Expert Picks
Mike McNamara
Mike McNamara
Last 30d: 85-89-0 (+4.3u)
ND +18.5-120
0.4u
Duck
Duck
Last 30d: 90-90-0 (-3.5u)
ND +18.5-120
0.55u
Doug Ziefel
Doug Ziefel
Last 30d: 160-179-2 (-8.7u)
Over 138.5-115
0.58u
JMann
JMann
Last 30d: 38-34-0 (+1.3u)
DUKE -15.5-110
1.5u
Duke’s elite defense against a ND offense without their 2 leading scorers in Burton and Harlason.

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Prop Odds Comparison

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Line Movement Tracker

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Duke vs. Notre Dame Public Betting Percentages

Away Logo

Duke

Public

55%

Bets%

45%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Notre Dame
14-137-87-55-68-7
Duke
15-129-96-311-101-0

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Notre Dame
17-1010-57-56-510-5
Duke
8-196-122-76-150-1

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Notre Dame
12-15N/AN/A9-22-13
Duke
25-2N/AN/A19-21-0

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Feb 21st@PITTL 68-73+3 LO 140PITT +130
Feb 14thGTW 89-74-5.5 WO 150.5ND -265
Feb 11th@SMUL 81-89+10.5 WO 154.5SMU +500
Feb 7thFSUL 79-82-1.5 LO 154.5FSU -120
Feb 5th@LOUL 65-76+18.5 WU 155.5LOU +1100

Duke vs. Notre Dame Injury Updates

Duke Injuries

  • Ifeanyi Ufochukwu
    C

    Ufochukwu is questionable with undisclosed

    Questionable

Notre Dame Injuries

  • Markus Burton
    G

    Burton is out with foot

    Out

  • Tommy Ahneman
    C

    Ahneman is out with knee

    Out

  • Jalen Haralson
    F

    Haralson is doubtful with undisclosed

    Doubtful

Team Stats
29-58 (50%)
Field Goals
26-58 (45%)
15-21 (71%)
Free Throws
13-19 (68%)
8-25 (32%)
3P
8-25 (32%)
36.85
Rebounds
33.7
17
Assists
12.4
10.48
Turnovers
10.74
8.04
Steals
4.7
3.52
Blocks
2.3
15.56
Fouls
17.41

Duke vs. Notre Dame Odds Comparison

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Duke at Notre Dame Team Totals

MatchupOverUnder
Duke
25-2
N/A
N/A
Notre Dame
12-15
N/A
N/A