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SMU vs. Vanderbilt Odds & Betting Predictions - December 4, 2025

SMU at Vanderbilt

2:15 am • SEC Network

Southern Methodist Mustangs

12-4
69
69 - 88

Vanderbilt Commodores

16-0
88

SMU at Vanderbilt Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
SMU
12-4
+9.5
+11-105
o166-110
+462
Vanderbilt
16-0
u167.5
-11-115
u166-110
-625
location pinThursday 2:15 a.m.
December 04, 2025
Memorial GymnasiumNashville
SMU vs. Vanderbilt Expert Picks
The Degenerates
The Degenerates
Last 30d: 96-87-2 (+1.4u)
Over 167-110
1.1u
The Pick Don
The Pick Don
Last 30d: 11-12-0 (-3.0u)
VAN -10.5-115
1u

SMU vs. Vanderbilt Previews & Analysis

  • SMU vs Vanderbilt: Why to Trust the Dores article feature image

    SMU vs Vanderbilt: Why to Trust the Dores

    Christian Odjakjian•
    Dec 3, 2025 UTC
  • How to Bet 5 ACC/SEC Challenge Matchups on Wednesday article feature image

    How to Bet 5 ACC/SEC Challenge Matchups on Wednesday

    Action Network Staff•
    Dec 3, 2025 UTC
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Prop Odds Comparison

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Line Movement Tracker

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SMU vs. Vanderbilt Public Betting Percentages

Away Logo

SMU

Public

Home Logo

Vanderbilt

22%

Bets%

78%

Money%

NCAAB Public Betting Right Arrow

Betting Trends

  • Vanderbilt are 5-0 in their last 5 games.
  • Vanderbilt are 4-1 in their last 5 games against the spread
  • Vanderbilt are 5-1 in their road games against the spread
  • The totals have gone OVER in 3 of Vanderbilt' last 5 games
  • The totals have gone OVER in 5 of Vanderbilt' 10 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Vanderbilt		10-65-55-19-3N/A
SMU		8-85-53-34-53-3

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Vanderbilt		9-75-54-26-6N/A
SMU		10-66-44-26-34-2

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Vanderbilt		16-0N/AN/A12-0N/A
SMU		12-4N/AN/A9-02-4

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Nov 28th@SMCW 96-71-4.5 WO 149.5VAN -192
Nov 27th@VCUW 89-74-6.5 WO 161.5VAN -285
Nov 26thWKUW 83-78-18.5 LU 168.5VAN -2449
Nov 21stTXSOW 109-74-36.5 LO 165.5-
Nov 15thARPBW 104-75-O 173-

Vanderbilt vs. SMU Injury Updates

Vanderbilt Injuries

  • Mike James
    G

    James is probable with knee

    Probable

  • Frankie Collins
    G

    Collins is out for season with foot

    Out for Season

SMU Injuries

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    Team Stats

    25-60 (42%)
    Field Goals
    36-63 (57%)
    17-23 (74%)
    Free Throws
    10-12 (83%)
    2-17 (12%)
    3P
    6-24 (25%)
    33
    Rebounds
    29
    12
    Assists
    20
    12
    Turnovers
    4
    2
    Steals
    7
    0
    Blocks
    8
    14
    Fouls
    21

    SMU vs. Vanderbilt Odds Comparison

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    SMU at Vanderbilt Team Totals

    MatchupOverUnder
    SMU
    12-4
    o76.5-120
    u76.5-110
    Vanderbilt
    16-0
    o89.5-105
    u89.5-125