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Red Wings vs. Sabres Odds & Betting Predictions - October 22, 2025

Red Wings at Sabres

11:30 pm • TNT

Detroit Red Wings

5-1-0
2
2 - 4

Buffalo Sabres

2-4-0
4

Red Wings at Sabres Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Red Wings
5-1-0
+1.5
+1.5-247
o6.5+105
-102
Sabres
2-4-0
u6.5
-1.5+195
u6.5-125
-122
location pinWednesday 11:30 p.m.
October 22, 2025
KeyBank CenterBuffalo
Red Wings vs. Sabres Expert Picks
VegasIsMyBitch
VegasIsMyBitch
Last 30d: 14-10-1 (+1.3u)
BUF +120 (Live)
0.6u
To Win in Regulation (No Overtime)
Bet Labs
Bet Labs
Last 30d: 15-18-0 (-3.4u)
Under 6.5-132
1u
The Degenerates
The Degenerates
Last 30d: 60-53-0 (+2.8u)
DET -110
1.1u
Picks Office
Picks Office
Last 30d: 88-72-3 (+10.8u)
DET +100
1u
X: PicksOffice
Scott Rickenbach
Scott Rickenbach
Last 30d: 95-113-2 (-29.5u)
BUF -110
0.91u
Nick Martin
Nick Martin
Last 30d: 36-43-0 (+7.3u)
T.Thompson Anytime Goal Scorer Yes+145
0.5u
https://www.dailyfaceoff.com/news/nhl-player-prop-bets-oct22
Allan Lem
Allan Lem
Last 30d: 126-98-5 (+8.0u)
B.Byram o0.5 Pts+185
0.26u
Tailing the ScoresAndOdds team
Lines at Lunch
Lines at Lunch
Last 30d: 95-110-4 (-24.0u)
BUF -104
1u

Red Wings vs. Sabres Previews & Analysis

  • Red Wings vs Sabres: A Moneyline Pick for Tonight article feature image

    Red Wings vs Sabres: A Moneyline Pick for Tonight

    Greg Liodice•
    Oct 22, 2025 UTC
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Prop Odds Comparison

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Line Movement Tracker

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Red Wings vs. Sabres Public Betting Percentages

Away Logo

Red Wings

Public

Home Logo

Sabres

61%

Bets%

39%

Money%

NHL Public Betting Right Arrow

Betting Trends

  • Sabres are 2-3 in their last 5 games.
  • Sabres are 2-3 in their last 5 games against the spread
  • Sabres are 0-2 in their road games against the spread
  • The totals have gone OVER in 1 of Sabres' last 5 games
  • The totals have gone OVER in 1 of Sabres' 4 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Sabres		2-42-20-2N/A2-4
Red Wings		5-14-11-00-15-0

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Sabres		1-51-30-2N/A1-5
Red Wings		2-42-30-10-12-3

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Sabres		2-4N/AN/AN/A2-4
Red Wings		5-1N/AN/A0-15-0

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Oct 20th@MTLL 2-4+1.5 LU 6.5MTL +124
Oct 18thFLAW 3-0+1.5 WU 5.5BUF +130
Oct 15thOTTW 8-4+1.5 WO 6.5BUF -110
Oct 13thCOLL 1-3+1.5 LU 6.5COL +152
Oct 11th@BOSL 1-3+1.5 LU 5.5BOS -104

Sabres vs. Red Wings Injury Updates

Sabres Injuries

  • Ukko-Pekka Luukkonen
    G

    Luukkonen is out with lower body

    Out

  • Joshua Norris
    C

    Norris is out with upper body

    Out

  • Jacob Bryson
    D

    Bryson is day-to-day with concussion

    Day-to-Day

  • Carson Meyer
    RW

    Meyer is out with knee

    Out

  • Michael Kesselring
    D

    Kesselring is out with lower body

    Out

  • Jordan Greenway
    LW

    Greenway is out with lower body

    Out

  • Justin Danforth
    RW

    Danforth is out with lower body

    Out

Red Wings Injuries

  • Patrick Kane
    RW

    Kane is out with upper body

    Out

See more NHL Injuries Right Arrow
Team Stats

2
Goals
4
4
Assists
8
5
Penalties
2
28
Shots
31
18
Hits
18
41
Faceoffs Won
32

Red Wings vs. Sabres Odds Comparison

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Red Wings at Sabres Team Totals

MatchupOverUnder
Red Wings
5-1-0
N/A
N/A
Sabres
2-4-0
N/A
N/A