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Padres vs. Tigers Odds & Betting Predictions - April 21, 2025

Padres at Tigers

10:40 pm • Fox Sports 1

San Diego Padres

4-5
4
4 - 6

Detroit Tigers

4-5
6
Starting Pitchers
pitcherteameraw-l
Keider Montero logoK.MonteroDetroit Tigers logo4.375-3
Randy Vasquez logoR.VasquezSan Diego Padres logo3.846-7

Padres at Tigers Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Padres
4-5
+1.5
+1.5-186
o8.5-107
+116
Tigers
4-5
u8.5
-1.5+142
u8.5-120
-148
location pinMonday 10:40 p.m.
April 21, 2025
Comerica ParkDetroit
Padres vs. Tigers Expert Picks
Kyle Just Bets
Kyle Just Bets
Last 30d: 0-0-0 (+0.0u)
R.Vasquez u3.5 Ks (Live)-128
0.39u
R.Vasquez u15.5 Outs (Live)-135
0.37u
Kyle Murray
Kyle Murray
Last 30d: 72-131-7 (-8.3u)
Z.McKinstry o1.5 Hits + Runs + RBIs-120
1u
R.Greene o1.5 Total Bases+120
1u
Collin Whitchurch
Collin Whitchurch
Last 30d: 78-131-2 (+7.4u)
SD +130 (F5)
0.5u
The Degenerate
The Degenerate
Last 30d: 0-0-0 (+0.0u)
Over 8.5-105
0.71u
Boomer Betz
Boomer Betz
Last 30d: 102-85-2 (+36.4u)
SD u3.5 Team Total+100
2u
#BQ
Doug Ziefel
Doug Ziefel
Last 30d: 216-292-16 (-17.9u)
R.Vasquez u15.5 Outs-150
0.5u
Ryan Minion
Ryan Minion
Last 30d: 225-268-1 (-5.7u)
F.Tatis o0.5 Doubles+330
$0.50
Shady Biev
Shady Biev
Last 30d: 0-0-0 (+0.0u)
SD +122
2u
Picks Office
Picks Office
Last 30d: 191-201-6 (-24.1u)
Under 8.5-115
1u
Padres' last 4 Vasquez starts: 0-4 to the under. ERA at 1.74, zero HRs allowed in 20.2 IP. Not a big strikeout guy, but elite soft contact – 14 hits total. Padres bullpen is dominant: 1.41 ERA, 0.87 WHIP. Suarez & Adam lights out late. SD tough to score on after 6th. Comerica plays big, suppresses runs. Tigers allow just 2.4 runs/game at home – starters holding a 1.61 ERA in Detroit. Montero shaky, but Detroit’s pen (3.04 ERA, 1.07 WHIP) solid at home. Kahnle (1.04 ERA), Holton (1.54) lead strong middle relief group. Quick hook likely. Padres’ road offense dips to 3.33 R/9 vs 4.67 overall. Under is 24-8-3 in Tigers’ last 35 at Comerica. Padres under in 10 of last 16 interleague. Tight matchup, elite pens, low HR park, and a starter in Vasquez who just doesn’t give up big innings.
Cam Is Money
Cam Is Money
Last 30d: 86-66-4 (+11.2u)
SD o1.5 Team Total (F5)-130
0.77u
Lines at Lunch
Lines at Lunch
Last 30d: 0-0-0 (+0.0u)
DET -0.5 (F5)-105
1u
Steak Friend
Steak Friend
Last 30d: 0-0-0 (+0.0u)
DET -142
1u
Sandy Plashkes
Sandy Plashkes
Last 30d: 131-136-6 (-20.4u)
DET -0.5 (F5)-104
1u
The Pick Don
The Pick Don
Last 30d: 12-5-0 (+8.5u)
DET -145 (F5)
1.5u
Billy Ward
Billy Ward
Last 30d: 22-32-1 (-4.0u)
Over 0.5 (1st Inn)-105
1u
Good to -115
Ryan Minion
Ryan Minion
Last 30d: 225-268-1 (-5.7u)
F.Tatis o1.5 Total Bases-120
$2.40
Capper Central
Capper Central
Last 30d: 0-0-0 (+0.0u)
Under 8.5-125
1.25u
Mjaybrod
Mjaybrod
Last 30d: 78-71-0 (+5.2u)
DET -130
0.77u
I bet (-123 on PX)
Brian Bitler
Brian Bitler
Last 30d: 59-76-2 (-56.7u)
SD +114
3u
Matt DiLeo
Matt DiLeo
Last 30d: 38-34-0 (-0.3u)
SD o1.5 Team Total (F5)-140
0.71u
Sean Zerillo
Sean Zerillo
Last 30d: 139-136-4 (+3.4u)
Under 8.5-115
0.58u
Bet to 8 (-105)

Padres vs. Tigers Previews & Analysis

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    Padres vs. Tigers: How to Bet the F5

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  • MLB NRFI & YRFI Predictions for Monday article feature image

    MLB NRFI & YRFI Predictions for Monday

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  • Zerillo's Monday MLB Predictions & Betting Card article feature image

    Zerillo's Monday MLB Predictions & Betting Card

    Sean Zerillo•
    Apr 21, 2025 UTC
  • 3 PRO Picks: Moneylines, Home Runs, K Props article feature image

    3 PRO Picks: Moneylines, Home Runs, K Props

    Action AI•
    Apr 21, 2025 UTC
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Prop Odds Comparison

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Line Movement Tracker

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Padres vs. Tigers Public Betting Percentages

Away Logo

Padres

Public

Home Logo

Tigers

59%

Bets%

41%

Money%

MLB Public Betting Right Arrow

Betting Trends

  • Tigers are 2-3 in their last 5 games.
  • Tigers are 2-3 in their last 5 games against the spread
  • Tigers are 2-4 in their road games against the spread
  • The totals have gone OVER in 2 of Tigers' last 5 games
  • The totals have gone OVER in 1 of Tigers' 3 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Tigers		4-52-12-43-21-2
Padres		5-43-32-13-12-3

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Tigers		4-4-11-1-13-32-2-11-2
Padres		3-5-12-3-11-20-3-13-2

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Tigers		4-52-12-43-21-2
Padres		4-52-42-12-22-3

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Apr 20thKCL 3-4-1.5 LU 7KC -225
Apr 19thKCW 3-1-1.5 WU 8DET -135
Apr 18thKCW 7-3+1.5 WO 7.5DET +120
Apr 17thKCW 6-1-1.5 WU 7.5DET -155
Apr 16th@MILL 1-5+1.5 LU 8.5MIL +131

Tigers vs. Padres Injury Updates

Tigers Injuries

  • Reese Olson
    SP

    Olson is out with shoulder

    Out

  • Jackson Jobe
    SP

    Jobe is out with elbow

    Out

  • Trey Sweeney
    SS

    Sweeney is out with shoulder

    Out

  • Sawyer Gipson-Long
    SP

    Gipson-Long is out with oblique

    Out

  • Beau Brieske
    RP

    Brieske is out with groin

    Out

  • Troy Melton
    SP

    Melton is out with elbow

    Out

Padres Injuries

  • Joe Musgrove
    SP

    Musgrove is out with elbow

    Out

  • Griffin Canning
    SP

    Canning is out with achilles

    Out

  • Matt Waldron
    SP

    Waldron is out with lower body

    Out

  • Will Wagner
    3B

    Wagner is out with oblique

    Out

See more MLB Injuries Right Arrow
Padres vs. Tigers Box Score
Padres Player Stats
Projected
PITCHERPCIPKER
Randy Vasquez logoRR.Vasquez, P68216
Logan Gillaspie logoRL.Gillaspie, P462.230
Wandy Peralta logoLW.Peralta, P131.100
Yuki Matsui logoLY.Matsui, P27210
HITTERSH-ABRHRRBI
Fernando Tatis logo1F.Tatis, RF1-5101
Gavin Sheets logo2G.Sheets, 1B2-4111
Manny Machado logo3M.Machado, 3B1-3100
Xander Bogaerts logo4X.Bogaerts, SS1-3000
Tirso Ornelas logo5T.Ornelas, LF0-2001
Joe logo5C.Joe, PH0-2000
Joe logo5C.Joe, LF0-2000
Oscar Gonzalez logo6O.Gonzalez, DH2-4001
Jose Iglesias logo7J.Iglesias, 2B0-3100
Wade logo8T.Wade, CF0-2000
Martin Maldonado logo9M.Maldonado, C0-3000
Yuli Gurriel logo9Y.Gurriel, PH0-1000
Tigers Player Stats
Projected
PITCHERPCIPKER
Keider Montero logoRK.Montero, P924.133
Brant Hurter logoLB.Hurter, P161.210
Brenan Hanifee logoRB.Hanifee, P26220
Will Vest logoRW.Vest, P10110
HITTERSH-ABRHRRBI
Gleyber Torres logo1G.Torres, 2B3-5102
Zach McKinstry logo2Z.McKinstry, RF3-4101
Riley Greene logo3R.Greene, LF1-4001
Spencer Torkelson logo4S.Torkelson, 1B1-4000
Colt Keith logo5C.Keith, DH1-2001
Justyn-Henry Malloy logo5J.Malloy, PH0-1000
Justyn-Henry Malloy logo5J.Malloy, DH0-1000
Jace Jung logo6J.Jung, 3B0-2100
Javier Baez logo7J.Baez, CF1-3100
Trey Sweeney logo8T.Sweeney, SS0-4100
Nido logo9T.Nido, C1-3101

Padres vs. Tigers Odds Comparison

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Padres at Tigers Team Totals

MatchupOverUnder
Padres
4-5
N/A
N/A
Tigers
4-5
N/A
N/A