Tigers vs. Guardians Odds & Betting Predictions - September 23, 2025

Tigers at Guardians

10:40 pm • CLEG

Detroit Tigers

14-13

2 - 5

Cleveland Guardians

15-12

pitcher		team	era	w-l
G.Williams			3.06	12-5
T.Skubal			2.21	13-6

MatchupOpenSpreadTotalMoneyline
Tigers 14-13	-1.5	-1.5+114	o6.5-120	-164
Guardians 15-12	u6.5	+1.5-139	u6.5+100	+136

Tuesday 10:40 p.m.

September 23, 2025

Progressive FieldCleveland

Under 6.5-102

1.02u

Under 6.5-105

1.05u

Under 3.5 (F5)-125

This is an absolutely massive series and it should be treated like a playoff game. We’ll see quick hooks for the pitchers if they get into trouble early, which bodes well for the under. Tarik Skubal seemed to be good to go after an injury scare, cruising through 6 innings of 1-run ball against Cleveland in his last start. The Guardians rank bottom 5 in OPS, wOBA, and wRC+ vs. LHP since the start of August. Gavin Williams tossed 5 scoreless innings against Detroit in his last start. He’s allowed a total of 4 ERs in his last 4 outings. Williams draws a Tigers’ lineup that ranks 25th or worse in OPS, wOBA, and wRC+ vs. RHP over the past 30 days.

Under 3.5 (F5)-125

CLE +1.5-144

0.69u

G.Williams o1.5 BB-175

0.57u

@cowhitchurch https://myaction.app/AW9nNvaRTWb

T.Skubal u1.5 Earned Runs-140

G.Williams o1.5 BB-175

0.5u

CLE +138

0.69u

CLE bullpen estimators best in MLB L30 days, DET 4th worst. The gap is larger than the one between Skubal and Williams' estimators - CLE better defense.

Tigers vs Guardians: Roaring in Cleveland
Tony Sartori•
Sep 23, 2025 UTC

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No props found

MLB Public Betting

Guardians are 3-2 in their last 5 games.
Guardians are 3-2 in their last 5 games against the spread
Guardians are 7-7 in their road games against the spread
The totals have gone OVER in 4 of Guardians' last 5 games
The totals have gone OVER in 6 of Guardians' 13 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Guardians	16-11	9-4	7-7	8-5	8-6
Tigers	13-14	8-4	5-10	9-9	4-4

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Guardians	14-13	6-7	8-6	7-6	7-7
Tigers	13-12-2	5-5-2	8-7	7-9-2	5-3

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Guardians	15-12	8-5	7-7	8-5	7-7
Tigers	14-13	10-2	4-11	11-7	3-5

date	opponent	score	spread	over/under	moneyline
Sep 21st	@MIN	L 2-6	-1.5 L	U 8.5	MIN -143
Sep 20th	@MIN	W 8-0	-1.5 W	U 8.5	CLE -108
Sep 20th	@MIN	W 6-0	-	-	-
Sep 20th	@MIN	W 6-2	-1.5 W	O 7.5	CLE -113
Sep 18th	@DET	W 3-1	+1.5 W	U 7	CLE +196

Steven Kwan
LF
Steven Kwan scratched Saturday
Out

Reese Olson
SP
Olson is out with shoulder
Out
Jackson Jobe
SP
Jobe is out with elbow
Out
Trey Sweeney
SS
Sweeney is out with shoulder
Out
Sawyer Gipson-Long
SP
Gipson-Long is out with oblique
Out
Beau Brieske
RP
Brieske is out with groin
Out
Troy Melton
SP
Melton is out with elbow
Out

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PITCHER	PC	IP	K	ER
LT.Skubal, P	95	6	8	1
RT.Kahnle, P	14	0.2	2	1
RK.Finnegan, P	16	0.1	0	1
LB.Hurter, P	7	0.2	0	0
RR.Montero, P	5	0.1	0	0

HITTERS	H-AB	R	HR	RBI
1P.Meadows, CF	0-4	0	0	0
2G.Torres, 2B	0-4	0	0	0
3K.Carpenter, DH	1-4	0	0	0
4S.Torkelson, 1B	0-3	0	0	0
5R.Greene, LF	2-4	1	1	1
6D.Dingler, C	0-3	0	0	0
7Z.McKinstry, 3B	1-4	1	0	0
7Z.McKinstry, SS	1-4	1	0	0
8W.Perez, RF	1-3	0	0	1
9T.Sweeney, SS	0-2	0	0	0
9A.Ibanez, PH	0-1	0	0	0
9A.Ibanez, 3B	0-1	0	0	0

PITCHER	PC	IP	K	ER
RG.Williams, P	91	6	12	2
LE.Sabrowski, P	10	1	2	0
RH.Gaddis, P	19	1	3	0
RC.Smith, P	9	1	2	0

HITTERS	H-AB	R	RBI
1S.Kwan, LF	2-4	2	0
2A.Martinez, CF	1-2	1	0
2D.Schneemann, PH	1-1	0	2
2D.Schneemann, RF	1-1	0	2
3J.Ramirez, 3B	1-3	1	1
4D.Fry, DH	0-3	0	0
4G.Valera, PH	0-1	0	0
4G.Valera, DH	0-1	0	0
5G.Arias, SS	0-3	0	1
6K.Manzardo, 1B	1-3	0	0
6P.Halpin, CF	1-1	0	0
7J.Noel, RF	0-3	0	0
7J.Noel, 1B	0-3	0	0
8B.Rocchio, 2B	0-3	0	0
9A.Hedges, C	0-2	1	0