Boston Col vs. Louisville Odds & Betting Predictions - October 25, 2025
Boston Col at Louisville
11:30 pm • ACC NetworkBoston Col at Louisville Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
Boston Col 1-10 | +22.5 | +25.5-110 | o54.5-110 | +1300 |
Louisville 7-4 | u53.5 | -25.5-110 | u54.5-110 | -2800 |

L&N Federal Credit Union StadiumLouisville
Boston Col vs. Louisville Expert Picks
FTN Fantasy
Last 30d: 118-146-3 (-39.1u)
LOU -12.5 (Live)-115
0.87u
LOU -14.5 (Live)-115
1u
The Degenerates
Last 30d: 83-82-2 (-5.4u)
LOU -25.5-105
1.05u
💰🦡 Jake
Last 30d: 87-107-4 (-14.2u)
BC +14.5 (1H)-114
1.5u
Boston Col vs. Louisville Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Boston Col vs. Louisville Public Betting Percentages
Betting Trends
- Louisville are 3-2 in their last 5 games.
- Louisville are 1-4 in their last 5 games against the spread
- Louisville are 3-1 in their road games against the spread
- The totals have gone OVER in 2 of Louisville' last 5 games
- The totals have gone OVER in 4 of Louisville' 7 last games at home
Matchup History
Against the Spread (ATS) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
| 3-8 | 0-7 | 3-1 | 2-7 | 1-1 | |
| 5-6 | 3-4 | 2-2 | 1-2 | 4-4 |
Over/Under History
| overall | home o/u | away o/u | favorite o/u | underdog o/u | |
|---|---|---|---|---|---|
| 5-6 | 4-3 | 1-3 | 5-4 | 0-2 | |
| 8-3 | 4-3 | 4-0 | 2-1 | 6-2 |
Straight-Up (ML) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
| 7-4 | N/A | N/A | 6-3 | 1-1 | |
| 1-10 | N/A | N/A | 1-2 | 0-8 |
Last 5 Matchups
Team Stats
360
Total Yards
504
82
Total Plays
59
4.390243902439025
Yards Per Play
8.542372881355933
244
YDS
187
23/46
Comps/Atts
15/28
5.304347826086956
YPA
6.678571428571429
3/2
TDs/INTs
1/1
2/13
Sacks/Yards
1/2
5/40
Penalties/Yards
6/45
Boston Col vs. Louisville Odds Comparison
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Boston Col at Louisville Team Totals
MatchupOverUnder | ||
|---|---|---|
Boston Col 1-10 | o13.5-130 | u13.5-101 |
Louisville 7-4 | o40.5-114 | u40.5-113 |






