Duke vs. Virginia Odds & Betting Predictions - December 7, 2025
Duke at Virginia
1:00 am • ABCDuke at Virginia Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
Duke 8-5 | +3.5 | +3.5-111 | o58.5-109 | +145 |
Virginia 10-3 | u58 | -3.5-109 | u58.5-111 | -180 |

Bank of America StadiumCharlotte
Duke vs. Virginia Expert Picks
Sir Lockselot
Last 30d: 38-58-0 (+5.3u)
DUKE +150
2.25u
📚Player Profit
Scott Rickenbach
Last 30d: 84-74-0 (+0.2u)
Over 58.5-108
1u
DUKE +3.5-109
0.92u
Collin Wilson
Last 30d: 47-32-1 (+10.7u)
DUKE +4-113
1u
Coming back on UVA live
YBK Picks.com
Last 30d: 35-34-0 (-4.6u)
UVA -3.5-105
3u
Vegas Refund
Last 30d: 33-33-0 (-3.4u)
DUKE +4-110
1u
Sandy Plashkes
Last 30d: 104-120-0 (-33.1u)
DUKE o27.5-110
1.1u
@Mjaybrxd
Mjaybrod
Last 30d: 78-61-1 (+18.3u)
DUKE o27.5-105
2u
Mensah to the moon
The Propfessor
Last 30d: 51-40-2 (+5.8u)
C.Morris o229.5 Pass Yds-114
1u
The Degenerates
Last 30d: 95-86-4 (+1.2u)
UVA -180
1.8u
Sandy Plashkes
Last 30d: 104-120-0 (-33.1u)
DUKE +4-110
1u
Mike Calabrese
Last 30d: 33-27-0 (+19.4u)
Over 79.5+750
0.25u
Available on FD
Duke has been playing in shootouts since the calendar turned to November. In the Blue Devils' past five games, the scoreboard has been lit up, averaging 71 points per contest. When the Duke offensive line protects Mensah, he’s a big-play triggerman. Duke finished 11th in big play creation, with 31 plays of 30+ yards from scrimmage (3rd-most in the ACC), and Mensah enters this ACC Title Bout as the 17th-best passer in the country from a QBR perspective (77.8). For this parlay to cash, I need him bombing away in catch-up mode. He’s used to that role, given Duke’s passing volume down the stretch. Mensah has been called upon to throw the ball 37 times per game since mid-October.
Now this whole thing only works if Virginia can set the pace early. The good news here is that UVA led the ACC in first-quarter scoring with 8.5 points in the first fifteen minutes of its games this fall. And this Duke defense is more than willing to lay down for the Wahoos. The Blue Devil secondary never recovered from the loss of Terry Moore at safety. You could make an argument that no secondary was worse in all of college football in the big play department, and Chandler Morris is primed to take advantage of that. He left meat on the bone the last time these two programs faced off, throwing for 300+ yards, but turning it over twice. Game flow also allowed UVA to take its foot off the accelerator. Had he been testing the Duke secondary for four quarters, 400 yards through the air, and 50 points were on the table.
Brian Bitler
Last 30d: 84-75-0 (+8.1u)
DUKE +4.5-115
2.61u
John Feltman
Last 30d: 65-55-1 (-9.0u)
Over 57.5-115
5.75u
Big Bets On Campus (CFB)
Last 30d: 56-57-1 (-3.0u)
UVA o30.5-125
1u
@_Collin1 https://myaction.app/SXl6WrC0QYb
J.Hasley Anytime TD Scorer Yes+280
1.01u
@_Collin1 https://myaction.app/SXl6WrC0QYb
💰🦡 Jake
Last 30d: 80-92-1 (-11.2u)
DUKE +3.5-110
1u
Collin Wilson
Last 30d: 47-32-1 (+10.7u)
UVA o30.5-115
1.15u
Full Writeup at ActionNetwork
J.Hasley Anytime TD Scorer Yes+275
1.51u
Hasley go-to red zone option last month; 22 total targets and 3 touchdowns past four games
Babs .
Last 30d: 94-64-0 (+24.4u)
DUKE +3.5-110
0.91u
Jeremiah Rose
Last 30d: 30-34-1 (-2.4u)
UVA -155
2.5u
Hedging Duke 15/1 Ticket - Wynn LV
Mike Calabrese
Last 30d: 33-27-0 (+19.4u)
UVA -3.5+105
3u
The college football world spent most of the season waiting for the other shoe to drop when it came to the Wahoos. Surely, a team that started 11-23 under Tony Elliott in his first three seasons couldn’t really compete for an ACC title, right? Some call it luck, others call it being clutch, but what we know is that Virginia is nails in tight ball games. The Cavaliers won three straight games this season by three points or less. Their only loss since early September came by seven to Wake Forest in a game in which Chandler Morris, UVA’s QB1, was knocked out with a head injury. In games that Morris has started and finished, UVA is 10-1 with its lone blemish coming to NC State in a shootout, 35-31.
Duke, meanwhile, backed its way into the ACC Title Game on the fifth tiebreaker (combined win percentage of ACC opponents). The Blue Devils went 3-3 down the stretch, allowing 29 points per game to their final six opponents. And in their head-to-head meeting with this very same Virginia team, the Blue Devils got blasted 34-17 while being outgained by 285 yards. At one point in the fourth quarter, it was 31-3 UVA. Simply put, it was one of the worst beatdowns the ACC produced all season long.
Sportsbooks are giving the Blue Devils a puncher’s chance because of their offense and Darian Mensah. When they protect him, he’s a big play triggerman. Duke finished 11th in big play creation, with 31 plays of 30+ yards from scrimmage (3rd-most in the ACC). So, how did UVA slow them down in their first meeting? With a nasty pass rush (4 sacks) and great situational playcalling by defensive coordinator John Rudzinski. Duke was just 4-for-15 on third downs, and the Blue Devils turned it over on downs twice, including once inside the UVA ten-yard line.
I’ll bank on a repeat performance in Charlotte from the Cavs.
Duke vs. Virginia Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Duke vs. Virginia Public Betting Percentages
Betting Trends
- Virginia are 3-2 in their last 5 games.
- Virginia are 3-2 in their last 5 games against the spread
- Virginia are 3-2 in their road games against the spread
- The totals have gone OVER in 3 of Virginia' last 5 games
- The totals have gone OVER in 4 of Virginia' 7 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Team Stats
Duke vs. Virginia Odds Comparison
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Duke at Virginia Team Totals
MatchupOverUnder | ||
|---|---|---|
Duke 8-5 | o27.5-110 | u27.5-120 |
Virginia 10-3 | o30.5-125 | u30.5-105 |






