Bills vs. Patriots Odds & Betting Predictions - December 14, 2025

Bills at Patriots

6:00 pm • CBS

Buffalo Bills

@

New England Patriots

MatchupOpenSpreadTotalMoneyline
Bills 8-4	-4.5	-1.5+102	o47.5-110	-112
Patriots 11-2	u46.5	+1.5-122	u47.5-110	-110

location pin

Sunday 6:00 p.m.

December 14, 2025

Gillette StadiumFoxborough

Under 48.5-110

1u

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NFL Public Betting

Patriots are 3-2 in their last 5 games.
Patriots are 3-2 in their last 5 games against the spread
Patriots are 5-1 in their road games against the spread
The totals have gone OVER in 2 of Patriots' last 5 games
The totals have gone OVER in 4 of Patriots' 7 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Patriots	9-4	4-3	5-1	6-3	3-1
Bills	6-6	3-3	3-3	4-6	2-0

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Patriots	7-6	4-3	3-3	5-4	2-2
Bills	5-7	4-2	1-5	4-6	1-1

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Patriots	11-2	N/A	N/A	8-1	3-1
Bills	8-4	N/A	N/A	6-4	2-0

date	opponent	score	spread	over/under	moneyline
Dec 2nd	NYG	W 33-15	-7 W	O 46.5	NE -372
Nov 23rd	@CIN	W 26-20	-7.5 L	U 50.5	NE -395
Nov 14th	NYJ	W 27-14	-12.5 W	U 43.5	NE -869
Nov 9th	@TB	W 28-23	+2.5 W	O 48.5	NE +127
Nov 2nd	ATL	W 24-23	-5.5 L	O 45.5	NE -250

Antonio Gibson
RB
Gibson is out with knee
Out

Charles Woods
CB
Woods is questionable with concussion
Questionable

Curtis Samuel
WR
Samuel is out with elbow
Out
Mecole Hardman
WR
Hardman is out with calf
Out
Tyler Bass
K
Bass is out with hip
Out
Joshua Palmer
WR
Palmer is questionable with ankle
Questionable
Dalton Kincaid
TE
Kincaid is questionable with hamstring
Questionable

See more NFL Injuries

passing yards
Drake Maye
3412
pyds
passing touchdowns
Drake Maye
23
ptd
rushing yards
TreVeyon Henderson
625
ryds
rushing touchdowns
TreVeyon Henderson
5
rtd

	Starter	2ND	3RD	4TH
QB	Drake Maye	Joshua Dobbs
RB	Rhamondre Stevenson	TreVeyon Henderson	Antonio Gibson	Terrell Jennings
WR	DeMario Douglas	Efton Chism	John Jiles
TE	Hunter Henry	Austin Hooper	Jack Westover	CJ Dippre
LT	Will Campbell	Vederian Lowe
LG	Jared Wilson
C	Garrett Bradbury	Ben Brown
RG	Mike Onwenu
RT	Morgan Moses	Caedan Wallace	Marcus Bryant
RDE	Milton Williams	Joshua Farmer
LCB	Carlton Davis	Alex Austin	Miles Battle
SS	Jaylinn Hawkins	Craig Woodson
FS	Brenden Schooler	Dell Pettus
RCB	Christian Gonzalez	Kobee Minor	Brandon Crossley
P	Bryce Baringer
H	Bryce Baringer
PR	Marcus Jones	DeMario Douglas
KR	TreVeyon Henderson	Antonio Gibson
LS	Julian Ashby
NT	Khyiris Tonga	Jeremiah Pharms
DT	Christian Barmore
RWR	Mack Hollins	Kyle Williams
NB	Marcus Jones
RILB	Christian Elliss	Jahlani Tavai
K	Andy Borregales
LILB	Robert Spillane	Jack Gibbens	Marte Mapu
LWR	Stefon Diggs	Kayshon Boutte	Jeremiah Webb
ROLB	Harold Landry	K'Lavon Chaisson	Bradyn Swinson	Elijah Ponder
LOLB	Anfernee Jennings

Total

Passing

2704

YDS

3246

246/356

Comps/Atts

277/388

8.107

YPA

8.825

19/10

TDs/INTs

23/6

28/182

Sacks/Yards

40/178

Rushing

1868

Rush Yards

1468

376

Attempts

376

4.968

YPC

3.904

21

TDs

12

Turnovers

Fumbles Lost

10

Interceptions

6

Efficiency

26/42 61.91%

Redzone

24/47 51.06%

66/149 0%

3rd Down

67/157 0%

10/17 0%

4th Down

14/18 0%

First Downs

264

Total

267

139

Pass

159

100

Rush

88

25

Penalty

20

Misc

/

Penalties/Yards

/

Possession

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MatchupOverUnder
Bills 8-4	N/A	N/A
Patriots 11-2	N/A	N/A