Turn your sports knowledge into winning predictions
21+ or 18+ in Certain Locations. 19+ in ON. Please Play Responsibly. Gambling Problem? Call 1-800-GAMBLER. Visit connexontario.ca or Call 1-866-531-2600 in ON.
No Code Needed

Colts vs. Chiefs Odds & Betting Predictions - November 23, 2025

Colts at Chiefs

6:00 pm • CBS

Indianapolis Colts

8-2
@

Kansas City Chiefs

5-5

Colts at Chiefs Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Colts
8-2
+9.5
+3.5-118
o50.5-108
+152
Chiefs
5-5
u45.5
-3.5-102
u50.5-110
-182
location pinSunday 6:00 p.m.
November 23, 2025
GEHA Field at Arrowhead StadiumKansas City
thermometer image57°Fahrenheit
rain image0%Rain
wind image5Wind
Colts vs. Chiefs Expert Picks
Sandy Plashkes
Sandy Plashkes
Last 30d: 112-126-6 (-16.4u)
KC -3-120
2.4u
Matt Moore
Matt Moore
Last 30d: 72-92-2 (-4.8u)
IND +3.5-114
1.14u
Brandon Kravitz
Brandon Kravitz
Last 30d: 77-83-2 (-0.7u)
KC -3-115
2.3u
As much as they screwed me last week from churning out my best NFL week to date by losing to Bo Nix…I’ve decided not to hold a grudge. My numbers spit out KC -4, early market reads indicate this line is going to close closer to 3.5, and matchup wise, I like Kansas City. Steve Spagnuolo will be copy and pasting (with a touch of his own spin) on what the Falcons did to Jones. 7 sacks, constant blitz, forcing multiple fumbles, and that was neutral site. This is at Arrowhead with the season on the line. Even though Indy has been great and they’re off the bye, KC is my first bet of the week - confidently.
Will Brinson
Will Brinson
Last 30d: 18-22-2 (-2.6u)
KC -3-118
1.18u
DK, no way the 3’s last long

Colts vs. Chiefs Previews & Analysis

See more NFL Coverage Right Arrow

Colts vs. Chiefs Props

Prop Projections

See All
Right Arrow

There are no prop projections found for the selected slate. Please check back later.

Prop Odds Comparison

Right Arrow
Right Arrow

No props found

Line Movement Tracker

Right Arrow
Right Arrow

Colts vs. Chiefs Public Betting Percentages

Away Logo

Colts

Public

Home Logo

Chiefs

58%

Bets%

42%

Money%

NFL Public Betting Right Arrow

Betting Trends

  • Chiefs are 3-2 in their last 5 games.
  • Chiefs are 3-2 in their last 5 games against the spread
  • Chiefs are 1-3 in their road games against the spread
  • The totals have gone OVER in 3 of Chiefs' last 5 games
  • The totals have gone OVER in 1 of Chiefs' 5 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Chiefs		5-54-11-34-41-1
Colts		6-44-12-24-32-1

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Chiefs		3-71-41-32-61-1
Colts		6-43-22-24-32-1

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Chiefs		5-5N/AN/A4-41-1
Colts		8-2N/AN/A6-12-1

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Nov 16th@DENL 19-22-4 LU 44.5DEN -216
Nov 2nd@BUFL 21-28-2.5 LU 53BUF -136
Oct 28thWASW 28-7-10.5 WU 48KC -590
Oct 19thLVW 31-0-13.5 WU 44.5KC -850
Oct 13thDETW 30-17-2.5 WU 51.5KC -150

Chiefs vs. Colts Injury Updates

Chiefs Injuries

  • Isiah Pacheco
    RB

    Pacheco is out with knee

    Out

  • Esa Pole
    OL

    Pole is out with ankle

    Out

Colts Injuries

  • George Odum
    S

    Odum is out with knee

    Out

See more NFL Injuries Right Arrow
Player Stats
  • passing yards
    Patrick Mahomes logo
    Patrick Mahomes
    2625
    pyds
  • passing touchdowns
    Patrick Mahomes logo
    Patrick Mahomes
    18
    ptd
  • rushing yards
    Kareem Hunt logo
    Kareem Hunt
    353
    ryds
  • rushing touchdowns
    Kareem Hunt logo
    Kareem Hunt
    6
    rtd
Depth Charts
Right Arrow
Starter2ND3RD4TH
QBPatrick MahomesGardner MinshewChris Oladokun
RBIsiah PachecoKareem HuntElijah MitchellBrashard Smith
WRRashee RiceNikko Remigio
TETravis KelceNoah GrayJared WileyRobert TonyanTre WatsonJake Briningstool
LTJosh SimmonsWanya MorrisEsa Pole
LGKingsley SuamataiaMike Caliendo
CCreed HumphreyHunter Nourzad
RGTrey SmithC.J. HansonEthan Driskell
RTJawaan TaylorJaylon MooreChukwuebuka Godrick
LDEGeorge KarlaftisCharles OmenihuMalik Herring
RDEMike DannaAshton Gillotte
WLBDrue TranquillJeffrey BassaCooper McDonald
MLBNick BoltonJack CochraneBrandon George
LCBJaylen WatsonNohl Williams
SSJaden HicksChamarri Conner
FSBryan CookMike Edwards
RCBKristian FultonNazeeh JohnsonJoshua Williams
PMatt Araiza
HMatt Araiza
PRNikko RemigioBrashard Smith
KRNikko RemigioBrashard Smith
LSJames Winchester
RWRMarquise BrownJalen RoyalsTyquan Thornton
FBCarson Steele
NTChris JonesJerry Tillery
KHarrison Butker
ROLBLeo ChenalCole Christiansen
LWRXavier WorthyJuJu Smith-SchusterJason Brownlee
DTMike PennelOmarr Norman-LottMarlon Tuipulotu
NBTrent McDuffieKevin KnowlesChris Roland-WallaceMelvin Smith
Team Stats

Passing

2516
YDS
2489
224/324
Comps/Atts
233/361
8.235
YPA
7.271
15/7
TDs/INTs
18/6
21/152
Sacks/Yards
20/136

Rushing

1453
Rush Yards
1153
274
Attempts
259
5.303
YPC
4.452
22
TDs
12

Turnovers

Fumbles Lost
7
Interceptions
6

Efficiency

30/44 68.18%
Redzone
27/41 65.85%
47/112 0%
3rd Down
52/126 0%
17/21 0%
4th Down
16/21 0%

First Downs

237
Total
224
131
Pass
130
87
Rush
78
19
Penalty
16

Misc

/
Penalties/Yards
/
Possession

Colts vs. Chiefs Odds Comparison

Right Arrow

Could not load odds

See more NFL Odds Right Arrow

Colts at Chiefs Team Totals

MatchupOverUnder
Colts
8-2
N/A
N/A
Chiefs
5-5
N/A
N/A