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Rams vs. Cardinals Odds & Betting Predictions - December 7, 2025

Rams at Cardinals

9:25 pm • FOX

Los Angeles Rams

9-3
@

Arizona Cardinals

3-9

Rams at Cardinals Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Rams
9-3
-8.5
-8-110
o48-110
-425
Cardinals
3-9
u48.5
+8-110
u48-110
+325
location pinSunday 9:25 p.m.
December 07, 2025
State Farm StadiumGlendale
thermometer image69°Fahrenheit
rain image0%Rain
wind image1Wind
Rams vs. Cardinals Expert Picks
Roger Goodell
Roger Goodell
Last 30d: 41-50-1 (-6.9u)
ARI +8.5-115
1u
FTN Fantasy
FTN Fantasy
Last 30d: 119-164-3 (-59.4u)
LA -7.5-110
1u

Rams vs. Cardinals Previews & Analysis

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Rams vs. Cardinals Props

Prop Projections

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Line Movement Tracker

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Rams vs. Cardinals Public Betting Percentages

Away Logo

Rams

Public

Home Logo

Cardinals

74%

Bets%

26%

Money%

NFL Public Betting Right Arrow

Betting Trends

  • Cardinals are 1-4 in their last 5 games.
  • Cardinals are 3-2 in their last 5 games against the spread
  • Cardinals are 5-1 in their road games against the spread
  • The totals have gone OVER in 2 of Cardinals' last 5 games
  • The totals have gone OVER in 5 of Cardinals' 6 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Cardinals		6-61-55-11-25-4
Rams		8-44-23-28-30-1

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Cardinals		7-55-12-42-15-4
Rams		5-71-54-14-71-0

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Cardinals		3-9N/AN/A2-11-8
Rams		9-3N/AN/A9-20-1

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Nov 30th@TBL 17-20+4.5 WU 45.5TB +185
Nov 23rdJACL 24-27+2.5 LO 47.5JAC +114
Nov 16thSFL 22-41+3.5 LO 48.5SF +157
Nov 9th@SEAL 22-44+7.5 LO 44.5SEA +285
Nov 4th@DALW 27-17+3.5 WU 53.5ARI +145

Rams vs. Cardinals Injury Updates

Rams Injuries

  • Tyler Higbee
    TE

    Higbee is out with ankle

    Out

Cardinals Injuries

  • Zay Jones
    WR

    Jones is out with achilles

    Out

  • James Conner
    RB

    Conner is out with foot

    Out

  • Kyler Murray
    QB

    Murray is out with foot

    Out

  • Emari Demercado
    RB

    Demercado is out with ankle

    Out

  • Marvin Harrison
    WR

    Harrison is questionable with heel

    Questionable

  • Trey Benson
    RB

    Benson is questionable with knee

    Questionable

  • Tip Reiman
    TE

    Reiman is out with ankle

    Out

See more NFL Injuries Right Arrow
Player Stats
  • passing yards
    Jacoby Brissett logo
    Jacoby Brissett
    2188
    pyds
  • passing touchdowns
    Jacoby Brissett logo
    Jacoby Brissett
    13
    ptd
  • rushing yards
    Bam Knight logo
    Bam Knight
    255
    ryds
  • rushing touchdowns
    Bam Knight logo
    Bam Knight
    4
    rtd
Depth Charts
Right Arrow
Starter2ND3RD4TH
QBKyler MurrayJacoby Brissett
RBJames ConnerTrey BensonEmari DemercadoMichael CarterZonovan Knight
WRGreg DortchZay JonesAndre Baccellia
TETrey McBrideTip ReimanElijah HigginsTravis VokolekJosiah Deguara
LTParis JohnsonKelvin Beachum
LGEvan Brown
CHjalte FroholdtJon Gaines
RGIsaiah AdamsWill HernandezHayden Conner
RTJonah WilliamsChristian JonesJosh FryarJeremiah Byers
LDECalais CampbellWalter NolenL.J. Collier
RDEDarius RobinsonJustin JonesBilal Nichols
WLBAkeem Davis-GaitherOwen Pappoe
MLBMack WilsonCody SimonJ.J. Russell
LCBWill JohnsonElijah Jones
SSJalen ThompsonDadrion Taylor-Demerson
FSBudda BakerJoey BlountKitan Crawford
RCBMax MeltonDenzel Burke
PBlake Gillikin
HBlake Gillikin
PRGreg DortchXavier Weaver
KRGreg DortchAndre Baccellia
LSAaron Brewer
NBGarrett WilliamsKei'Trel ClarkDarren Hall
NTDalvin TomlinsonDante StillsPJ Mustipher
LWRMarvin HarrisonSimi FehokoTejhaun Palmer
ROLBJosh SweatBJ Ojulari
KChad Ryland
LOLBBaron BrowningZaven CollinsJordan BurchElliott Brown
RWRMichael WilsonXavier Weaver
Team Stats

Passing

2959
YDS
2840
266/402
Comps/Atts
315/465
7.644
YPA
6.77
32/4
TDs/INTs
19/7
17/114
Sacks/Yards
42/308

Rushing

1362
Rush Yards
1207
310
Attempts
280
4.394
YPC
4.311
10
TDs
9

Turnovers

Fumbles Lost
4
Interceptions
7

Efficiency

35/53 66.04%
Redzone
27/47 57.45%
49/126 0%
3rd Down
70/163 0%
13/19 0%
4th Down
7/18 0%

First Downs

269
Total
248
160
Pass
156
82
Rush
70
27
Penalty
22

Misc

/
Penalties/Yards
/
Possession

Rams vs. Cardinals Odds Comparison

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Rams at Cardinals Team Totals

MatchupOverUnder
Rams
9-3
N/A
N/A
Cardinals
3-9
N/A
N/A