Astros vs. Guardians Odds & Betting Predictions - June 7, 2025

Astros at Guardians

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Starting Pitchers
pitcherteameraw-l
Gavin Williams logoG.WilliamsCleveland Guardians logo3.795-3
Hunter Brown logoH.BrownHouston Astros logo1.838-3

Astros at Guardians Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Astros
35-28
-1.5
-1.5+145
o7-108
-118
Guardians
33-29
u7
+1.5-176
u7-111
-103
location pinSaturday 8:10 p.m.
June 07, 2025
Progressive FieldCleveland
thermometer image72°Fahrenheit
rain image0%Rain
wind image9Wind
Astros vs. Guardians Expert Picks
Steak Friend
Steak Friend
Last 30d: 134-153-1 (-28.6u)
CLE -103
1.03u
YBK Picks.com
Last 30d: 32-26-4 (+6.1u)
CLE -105
2u
Ray  Monohan
Ray Monohan
Last 30d: 7-9-0 (-1.6u)
CLE -102
0.75u
Picks Office
Picks Office
Last 30d: 77-74-0 (+2.5u)
CLE +105
1u
Wind blowing in 9.2 MPH at Progressive favors the arms – helps suppress Houston’s bats. Astros cooling off: .270 wOBA & 68 wRC+ over last 7 days, both bottom 6 in MLB. Hunter Brown’s still elite but 2.51 road ERA is nearly a full run higher than at home – regression looming. Gavin Williams locked in – 2.30 ERA over last 5 starts. Guardians 4-2 in his home starts. Last outing: 6.2 scoreless, 1 hit vs Angels. Houston’s .253 AVG hiding inefficiency – just 4.03 runs/game (22nd MLB). Cleveland thrives in small-ball spots: bunts, sac flies, situational ABs. Ramírez is the X-factor – .330 AVG, 11 HRs, elite RISP bat. Guardians’ pen underrated, 3.82 ERA (15th) but clutch in close games. Day game + home underdog vibes = edge in motivation. Cleveland’s urgency > Houston’s pressure. Astros won 7 of 8 vs CLE? Payback time.
💰🦡 Jake
💰🦡 Jake
Last 30d: 85-77-5 (+7.6u)
HOU -1.5+150
1u
Sandy Plashkes
Sandy Plashkes
Last 30d: 104-109-7 (-1.0u)
CLE +104
1u

Astros vs. Guardians Previews & Analysis

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Prop Odds Comparison

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Line Movement Tracker

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Astros vs. Guardians Public Betting Percentages

Away Logo

Astros

Public

66%

Bets%

34%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Guardians
30-3214-1516-1711-1119-20
Astros
34-2918-1616-1319-2415-4

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Guardians
26-33-312-16-114-17-212-1014-22-3
Astros
25-36-214-2011-16-221-223-14-2

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Guardians
33-2917-1216-1715-718-21
Astros
35-2822-1213-1624-1911-8

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Jun 6thHOUL 2-4+1.5 LU 8HOU +110
Jun 5th@NYYL 0-4+1.5 LU 8.5NYY +225
Jun 4th@NYYW 4-0+1.5 WU 9CLE +164
Jun 3rd@NYYL 2-3+1.5 WU 8NYY +166
Jun 1stLAAW 4-2-1.5 WU 8CLE -210

Guardians vs. Astros Injury Updates

Guardians Injuries

  • Ben Lively
    P

    Lively is out with elbow

    Out

  • Shane Bieber
    P

    Bieber is out with elbow

    Out

  • John Means
    P

    Means is out with elbow

    Out

Astros Injuries

  • Taylor Trammell
    OF

    Trammell is out with calf

    Out

  • Cristian Javier
    P

    Javier is out with elbow

    Out

  • Luis Garcia
    P

    Garcia is out with elbow

    Out

  • Pedro Leon
    OF

    Leon is out with knee

    Out

  • J.P. France
    P

    France is out with shoulder

    Out

  • Hayden Wesneski
    P

    Wesneski is out with elbow

    Out

  • Spencer Arrighetti
    P

    Arrighetti is out with thumb

    Out

Astros vs. Guardians Starting Lineups
Astros Starting Lineup
Projected
PITCHERW-LERAWHIPK/9
Hunter Brown logoRH.Brown, P8-31.830.90910.26
HITTERSAVGOBPSLGHR
Jeremy Pena logo1J.Pena, SS.324.382.4949
Isaac Paredes logo2I.Paredes, 3B.254.356.47414
Jose Altuve logo3J.Altuve, LF.267.312.4049
Christian Walker logo4C.Walker, 1B.210.274.3588
Victor Caratini logo5V.Caratini, DH.264.338.3883
Yainer Diaz logo6Y.Diaz, C.227.263.3677
Jake Meyers logo7J.Meyers, CF.286.346.3963
Mauricio Dubon logo8M.Dubon, RF.257.291.3431
Brendan Rodgers logo9B.Rodgers, 2B.194.270.2912
Guardians Starting Lineup
Projected
PITCHERW-LERAWHIPK/9
Gavin Williams logoRG.Williams, P5-33.791.44910.01
HITTERSAVGOBPSLGHR
Steven Kwan logo1S.Kwan, LF.306.367.4265
Angel Martinez logo2A.Martinez, CF.246.264.3774
Jose Ramirez logo3J.Ramirez, DH.329.382.54411
Kyle Manzardo logo4K.Manzardo, 1B.210.299.44111
Daniel Schneemann logo5D.Schneemann, 2B.254.335.4577
Gabriel Arias logo6G.Arias, SS.236.300.3574
Bo Naylor logo7B.Naylor, C.175.286.3717
Nolan Jones logo8N.Jones, RF.219.294.3152
Will Wilson logo9W.Wilson, 3B.200.294.2670

Astros vs. Guardians Odds Comparison

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Astros at Guardians Team Totals

MatchupOverUnder
Astros
35-28
N/A
N/A
Guardians
33-29
N/A
N/A