Padres vs. Cubs Odds & Betting Predictions - September 30, 2025

Padres at Cubs

7:08 pm • ABC
1 - 3
Starting Pitchers
pitcherteameraw-l
Matthew Boyd logoM.BoydChicago Cubs logo0.000-0
Nicholas Pivetta logoN.PivettaSan Diego Padres logo0.000-0

Padres at Cubs Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Padres
1-1
-1.5
+1.5-210
o6.5-114
+112
Cubs
1-1
u7
-1.5+173
u6.5-105
-133
location pinTuesday 7:08 p.m.
September 30, 2025
Wrigley FieldChicago
Padres vs. Cubs Expert Picks
Kyle Murray
Kyle Murray
Last 30d: 53-50-3 (+7.5u)
CHC -125
1u
Under 3.5 (F5)+100
1u
Scott Rickenbach
Scott Rickenbach
Last 30d: 52-50-2 (-6.2u)
CHC -130
0.77u
Cam Is Money
Cam Is Money
Last 30d: 56-70-3 (-13.3u)
SD +115
1u
Wags Wins
Wags Wins
Last 30d: 172-150-1 (+17.1u)
SD +115
1u
💰🦡 Jake
💰🦡 Jake
Last 30d: 100-123-6 (+29.3u)
Over 3.5 (F5)-120
1.2u
YBK Picks.com
Last 30d: 42-38-2 (+2.4u)
CHC -130
1.54u
Lines at Lunch
Lines at Lunch
Last 30d: 94-92-3 (-4.4u)
M.Machado o1.5 Hits + Runs + RBIs-130
1.3u
M.Busch o1.5 Total Bases+142
0.7u
Ryan Sura
Ryan Sura
Last 30d: 100-95-2 (+6.7u)
M.Busch o1.5 Total Bases+142
1u
Kenny Ducey
Kenny Ducey
Last 30d: 29-25-2 (+2.3u)
CHC -130
1u
Picks Office
Picks Office
Last 30d: 60-82-3 (-18.6u)
CHC -120
0.83u
Lines at Lunch
Lines at Lunch
Last 30d: 94-92-3 (-4.4u)
M.Boyd o4.5 Hits Allowed-129
1.29u
SD +102
0.98u
Sandy Plashkes
Sandy Plashkes
Last 30d: 75-104-3 (-10.5u)
SD +102
1u
Boomer Betz
Boomer Betz
Last 30d: 123-106-2 (+20.6u)
CHC -108
0.93u
Cam Is Money
Cam Is Money
Last 30d: 56-70-3 (-13.3u)
M.Boyd u3.5 Ks+120
1.2u
Moneyline Hacks
Moneyline Hacks
Last 30d: 112-131-7 (+45.0u)
Under 7-109
0.92u
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Payoff Pitch Podcast
Payoff Pitch Podcast
Last 30d: 65-77-6 (+8.9u)
N.Pivetta u14.5 Outs+127
1u
M.Machado To Hit 1+ Home Runs Yes+466
0.25u
M.Machado To Record 2+ Total Bases Yes+113
1u
CHC -110
0.91u
Under 7-106
0.94u
M.Boyd u14.5 Outs+140
1.4u
Sean Zerillo
Sean Zerillo
Last 30d: 149-175-5 (-13.2u)
CHC -110
0.5u
Bet to -125. Split with series price
Under 7-106
0.5u
Bet to -110
M.Boyd u14.5 Outs+155
0.16u
Bet to +125
N.Pivetta u14.5 Outs+139
0.1u
Bet to +120

Padres vs. Cubs Previews & Analysis

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See more MLB Coverage Right Arrow

Prop Odds Comparison

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Line Movement Tracker

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Padres vs. Cubs Public Betting Percentages

Away Logo

Padres

Public

50%

Bets%

50%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Cubs
79-8336-4543-3833-5045-32
Padres
82-7835-4547-3343-5737-19

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Cubs
75-81-634-46-141-35-540-39-434-41-2
Padres
81-74-544-34-237-40-351-44-528-28

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Cubs
92-7044-3739-4245-3837-40
Padres
4-345-3547-3358-4231-25

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Sep 28thSTLW 2-0-1.5 WU 7CHC -155
Sep 27thSTLW 7-3-1.5 WO 9.5CHC -178
Sep 26thSTLW 12-1-1.5 WO 9CHC -184
Sep 25thNYML 5-8+1.5 LO 7.5NYM -103
Sep 25thNYMW 10-3+1.5 WO 7.5CHC -118

Cubs vs. Padres Injury Updates

Cubs Injuries

  • Michael Soroka
    SP

    Soroka is out with shoulder

    Out

  • Justin Steele
    SP

    Steele is out for season with elbow

    Out for Season

Padres Injuries

  • Joseph Musgrove
    SP

    Musgrove is out for season with elbow

    Out for Season

Padres vs. Cubs Box Score
Padres Player Stats
Projected
PITCHERPCIPKER
Nicholas Pivetta logoRN.Pivetta, P85592
Adrian Morejon logoLA.Morejon, P9100
Mason Miller logoRM.Miller, P13130
Jeremiah Estrada logoRJ.Estrada, P100.201
Wandy Peralta logoLW.Peralta, P60.110
HITTERSH-ABRHRRBI
Fernando Tatis logo1F.Tatis, RF0-4000
Luis Arraez logo2L.Arraez, 1B0-4000
Manuel Machado logo3M.Machado, 3B0-3000
Jackson Merrill logo4J.Merrill, CF1-3100
Xander Bogaerts logo5X.Bogaerts, SS2-4001
Ryan O'Hearn logo6R.O'Hearn, DH0-3000
Gavin Sheets logo7G.Sheets, LF0-3000
Jacob Cronenworth logo8J.Cronenworth, 2B0-3000
Freddy Fermin logo9F.Fermin, C1-3000
Cubs Player Stats
Projected
PITCHERPCIPKER
Matthew Boyd logoLM.Boyd, P584.121
Daniel Palencia logoRD.Palencia, P171.220
Thomas Pomeranz logoLD.Pomeranz, P11100
Andrew Kittredge logoRA.Kittredge, P14110
Brad Keller logoRB.Keller, P13110
HITTERSH-ABRHRRBI
Michael Busch logo1M.Busch, 1B1-3000
Nicholas Hoerner logo2N.Hoerner, 2B2-3001
Ian Happ logo3I.Happ, LF0-4000
Kyle Tucker logo4K.Tucker, DH0-3000
Seiya Suzuki logo5S.Suzuki, RF1-3111
Carson Kelly logo6C.Kelly, C1-3111
Peter Crow-Armstrong logo7P.Crow-Armstrong, CF0-3000
Dansby Swanson logo8D.Swanson, SS1-3100
Matthew Shaw logo9M.Shaw, 3B0-2000

Padres vs. Cubs Odds Comparison

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Padres at Cubs Team Totals

MatchupOverUnder
Padres
1-1
o2.5-155
u2.5+120
Cubs
1-1
o3.5+110
u3.5-140