Padres vs. Cubs Odds & Betting Predictions - October 1, 2025
Padres at Cubs
7:08 pm • ABCStarting Pitchers
pitcher | team | era | w-l | |
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![]() | ![]() | 0.00 | 0-0 | |
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Padres at Cubs Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
---|---|---|---|---|
![]() Padres 1-1 | -1.5 | -1.5+163 | o6.5-111 | -111 |
![]() Cubs 1-1 | u7 | +1.5-203 | u6.5-107 | -110 |

Wrigley FieldChicago
Padres vs. Cubs Expert Picks

Boomer Betz
Last 30d: 123-106-2 (+20.6u)
CHC +148 (Live)
1u
Scott Rickenbach
Last 30d: 52-50-2 (-6.2u)
Over 6.5 (Live)-116
1u

VegasIsMyBitch
Last 30d: 9-16-0 (-4.0u)
Under 6.5-105
0.95u

Kyle Murray
Last 30d: 53-50-3 (+7.5u)
Under 3.5 (F5)-125
1u

The Degenerates
Last 30d: 75-64-2 (+5.8u)
Under 6.5-110
1u

Kyle Murray
Last 30d: 53-50-3 (+7.5u)
D.Cease u5.5 Ks+112
1.12u
CHC -115
1.15u

Allan Lem
Last 30d: 113-113-8 (-4.3u)
Under 6.5+100
1u
Both bullpens are above-average and I’m expecting Imanaga to come in as the bulk pitcher for Chicago to help against the lefties in the bottom of the lineup.
Padres facing elimination so should be a quick hook for Cease if he’s ineffective or runs into trouble. Winds projected to be blowing in. All these factors have me on the Under 6.5 here.

Charlie Wright
Last 30d: 15-12-0 (+1.8u)
A.Kittredge u0.5 Ks+205
1u
Since getting traded to Chicago, Kittredge has made 23 appearances. All of them were 1 inning or less. He pitched in Game 1, covering a single inning.
Kittredge has bumped his strikeout rate to a career-high 30.8% by spamming his slider. He's thrown the pitch 52.9% of the time, and it has an excellent 40.3% whiff rate.
San Diego makes a ton of contact. They had the 3rd-lowest K% vs. RHP in the regular season. Tatis (18.9% K% against RHP this season), Luis Arraez (2.3%), and Manny Machado (19.5%) will be the first three hitters in the lineup. Their strikeout numbers against specifically right-handed sliders are in line with their season-long marks, so they shouldn't be overly susceptible to Kittredge's main pitch.

Kenny Ducey
Last 30d: 29-25-2 (+2.3u)
CHC -116
1.16u
Obligatory Cease fade
YBK Picks.com
Last 30d: 42-38-2 (+2.4u)
Under 6.5-115
1.74u

💰🦡 Jake
Last 30d: 100-123-6 (+29.3u)
SD o3.5+124
1u

Lines at Lunch
Last 30d: 94-92-3 (-4.4u)
Over 3.5 (F5)+105
0.95u

Ryan Sura
Last 30d: 100-95-2 (+6.7u)
Over 3.5 (F5)+105
1u

Lines at Lunch
Last 30d: 94-92-3 (-4.4u)
SD -102
1u

Payoff Pitch Podcast
Last 30d: 65-77-6 (+8.9u)
CHC -110
1u
@Zerillo
D.Cease u14.5 Outs-115
0.87u
@Zerillo @cowhitchurch https://myaction.app/irmZJtM46Wb

Cam Is Money
Last 30d: 56-70-3 (-13.3u)
CHC -113
1u

Sean Zerillo
Last 30d: 149-175-5 (-13.2u)
D.Cease u14.5 Outs-141
0.1u
Bet to -155

Lines at Lunch
Last 30d: 94-92-3 (-4.4u)
SD +102
1u

Brian Bitler
Last 30d: 74-73-1 (-5.5u)
CHC -112
3u

Anders
Last 30d: 11-14-0 (-2.6u)
CHC -106
1.06u
Analysis on Tiktok… I’d play to -120

Brandon Kravitz
Last 30d: 45-54-0 (-5.4u)
Under 6.5+100
1u

Sandy Plashkes
Last 30d: 75-104-3 (-10.5u)
SD +102
1.02u

Sean Zerillo
Last 30d: 149-175-5 (-13.2u)
CHC -104
1.04u
Bet to -115
Padres vs. Cubs Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Padres vs. Cubs Public Betting Percentages
Betting Trends
- Cubs are 3-2 in their last 5 games.
- Cubs are 2-3 in their last 5 games against the spread
- Cubs are 43-38 in their road games against the spread
- The totals have gone OVER in 2 of Cubs' last 5 games
- The totals have gone OVER in 34 of Cubs' 81 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Cubs vs. Padres Injury Updates

Cubs Injuries
- Michael SorokaSP
Soroka is out with shoulder
Out
- Justin SteeleSP
Steele is out for season with elbow
Out for Season

Padres Injuries
- Joseph MusgroveSP
Musgrove is out for season with elbow
Out for Season
Padres vs. Cubs Box Score

PITCHER | PC | IP | K | ER | |
---|---|---|---|---|---|
![]() | 69 | 3.2 | 5 | 0 | |
![]() | 33 | 2.1 | 1 | 0 | |
![]() | 27 | 1.2 | 5 | 0 | |
![]() | 18 | 1.1 | 0 | 0 |
HITTERS | H-AB | R | HR | RBI |
---|---|---|---|---|
![]() | 1-4 | 2 | 0 | 0 |
![]() | 2-3 | 0 | 0 | 0 |
![]() | 1-4 | 1 | 1 | 2 |
![]() | 0-2 | 0 | 0 | 1 |
![]() | 1-4 | 0 | 0 | 0 |
![]() | 1-3 | 0 | 0 | 0 |
![]() | 0-1 | 0 | 0 | 0 |
![]() | 0-1 | 0 | 0 | 0 |
![]() | 0-2 | 0 | 0 | 0 |
![]() | 0-4 | 0 | 0 | 0 |
![]() | 1-4 | 0 | 0 | 0 |

PITCHER | PC | IP | K | ER | |
---|---|---|---|---|---|
![]() | 20 | 1 | 1 | 1 | |
![]() | 67 | 4 | 3 | 2 | |
![]() | 14 | 0.2 | 1 | 0 | |
![]() | 15 | 1.2 | 1 | 0 | |
![]() | 13 | 1 | 0 | 0 | |
![]() | 6 | 0.2 | 0 | 0 |
HITTERS | H-AB | R | HR | RBI |
---|---|---|---|---|
![]() | 0-3 | 0 | 0 | 0 |
![]() | 1-4 | 0 | 0 | 0 |
![]() | 0-4 | 0 | 0 | 0 |
![]() | 1-4 | 0 | 0 | 0 |
![]() | 1-4 | 0 | 0 | 0 |
![]() | 0-2 | 0 | 0 | 0 |
![]() | 0-3 | 0 | 0 | 0 |
![]() | 1-3 | 0 | 0 | 0 |
![]() | 0-2 | 0 | 0 | 0 |
![]() | 0-1 | 0 | 0 | 0 |
![]() | 0-0 | 0 | 0 | 0 |
Padres vs. Cubs Odds Comparison
Could not load odds
Padres at Cubs Team Totals
MatchupOverUnder | ||
---|---|---|
![]() Padres 1-1 | o3.5+115 | u3.5-146 |
![]() Cubs 1-1 | o2.5-160 | u2.5+124 |