Yankees vs. Guardians Odds & Betting Predictions - April 21, 2025
Yankees at Guardians
10:10 pm • YESStarting Pitchers
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Yankees at Guardians Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
---|---|---|---|---|
![]() Yankees 13-7 | N/A | N/A | N/A | |
![]() Guardians 10-9 | N/A | N/A | N/A |

Progressive FieldCleveland
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Prop Odds Comparison
Line Movement Tracker
Yankees vs. Guardians Public Betting Percentages
Betting Trends
- Guardians are 2-3 in their last 5 games.
- Guardians are 2-3 in their last 5 games against the spread
- Guardians are 5-8 in their road games against the spread
- The totals have gone OVER in 2 of Guardians' last 5 games
- The totals have gone OVER in 2 of Guardians' 6 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Guardians vs. Yankees Injury Updates

Guardians Injuries
- Shane BieberP
Bieber is out with elbow
Out
- Slade CecconiP
Cecconi is out with oblique
Out
- John MeansP
Means is out with elbow
Out
- David FryC
Fry is out with elbow
Out

Yankees Injuries
- Gerrit ColeP
Cole is out for season with elbow
Out for Season
- DJ LeMahieuIF
LeMahieu is out with calf
Out
- Giancarlo StantonDH
Stanton is out with elbow
Out
- Luis GilP
Gil is out with back
Out
- JT BrubakerP
Brubaker is out with ribs
Out
Yankees vs. Guardians Odds Comparison
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Yankees at Guardians Team Totals
MatchupOverUnder | ||
---|---|---|
![]() Yankees 13-7 | N/A | N/A |
![]() Guardians 10-9 | N/A | N/A |