Yankees vs. Guardians Odds & Betting Predictions - April 22, 2025

Yankees at Guardians

10:10 pm • CLEG
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Starting Pitchers
pitcherteameraw-l
Tanner Bibee logoT.BibeeCleveland Guardians logo5.851-2
Will Warren logoW.WarrenNew York Yankees logo5.171-0

Yankees at Guardians Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Yankees
14-9
-1.5
-1.5+157
o8.5-115
-104
Guardians
13-9
u8
+1.5-189
u8.5-105
-115
location pinTuesday 10:10 p.m.
April 22, 2025
Progressive FieldCleveland
thermometer image57°Fahrenheit
rain image0%Rain
wind image4Wind
Yankees vs. Guardians Expert Picks
Steak Friend
Steak Friend
Last 30d: 217-221-6 (+12.7u)
Over 8.5-115
1.15u
Firefighter Bets
Firefighter Bets
Last 30d: 192-204-2 (-10.9u)
A.Judge o1.5 Hits + Runs + RBIs-130
1u
Shady Biev
Shady Biev
Last 30d: 63-80-0 (+4.7u)
NYY -113
2.26u
Grant Neiffer
Grant Neiffer
Last 30d: 34-98-5 (+16.3u)
J.Ramirez o0.5 HR+560
0.97u
K.Manzardo o0.5 HR+575
0.5u
Picks Office
Picks Office
Last 30d: 91-75-4 (+11.3u)
Under 8+100
1u
Guardians offense light – 4.18 runs/game, .235 AVG overall, .237 vs RHP. Warren keeps it on the ground – 2.00 GB/FB ratio limits big innings. Progressive Field low scoring – just 7.3 total runs/game. Early season trends lean low-scoring battle. Yankees bullpen in form – 2.45 ERA, 1.03 WHIP over last 3, 33 Ks in 33 IP. Starters likely won’t go deep, so pens matter. Both squads have reliable late arms. If this stays tight, expect minimal scoring from the 6th on. Yankees offense can flash but still averaging just 5.65 runs. Guardians stingy at home – 1.86 ERA, 6-1 at Progressive. Past 8 for Yankees hit the under in 5. Low tempo, contact-heavy matchups, both teams capable of limiting damage.
NYY -105
1u
Yankees’ pen rolling – 2.45 ERA, 1.03 WHIP over last 33 IP. Full unit at 3.30 ERA, 1.15 WHIP on the year – deeper, sharper group than Cleveland’s. If it's close late, edge clearly NY. Warren solid enough – 2.00 GB/FB ratio, limits HRs, team 2-1 in his last 3. Guardians hitting just .237 vs RHP, so he’s in a good spot to keep them quiet. Just needs to go 5+ and hand it off. Cleveland offense doesn’t scare, especially if it’s tight early. Bibee in a rough patch – 8.16 ERA, 7 HR allowed last 14.1 IP. Yankees will attack. Judge leading the charge (.494 xwOBA, 59.4% Hard Hit). NY hitting .252 vs RHP, averaging 5.65 runs/game – more firepower across the board. They’ve won 15 of last 22 in Cleveland.
Lines at Lunch
Lines at Lunch
Last 30d: 63-57-7 (+0.4u)
NYY o4.5 Team Total+105
0.95u
Ray  Monohan
Ray Monohan
Last 30d: 12-8-1 (+2.0u)
Over 8.5-110
0.75u
Top Shelf Action 🥃
Top Shelf Action 🥃
Last 30d: 407-592-16 (-16.5u)
J.Dominguez o0.5 HR+870
0.1u
Capper Central
Capper Central
Last 30d: 117-75-13 (+35.8u)
Under 8.5-125
1.35u
Allan Lem
Allan Lem
Last 30d: 75-50-2 (+5.4u)
T.Bibee u5.5 Ks+115
0.43u
Tailing @TurveyBets
Cam Is Money
Cam Is Money
Last 30d: 100-109-4 (-10.4u)
CLE -112
1u

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Prop Odds Comparison

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Line Movement Tracker

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Yankees vs. Guardians Public Betting Percentages

Away Logo

Yankees

Public

74%

Bets%

26%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Guardians
10-124-36-95-35-8
Yankees
12-118-44-711-81-3

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Guardians
11-9-23-48-5-25-36-5-2
Yankees
12-9-27-55-4-210-8-12-1-1

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Guardians
13-96-17-87-16-7
Yankees
14-98-46-513-61-3

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Apr 21stNYYW 6-4+1.5 WO 8.5CLE +110
Apr 20th@PITW 5-4-1.5 LO 8CLE +105
Apr 19th@PITW 3-0+1.5 WU 8CLE +145
Apr 18th@PITW 10-7-1.5 WO 9CLE -130
Apr 17th@BALL 2-6+1.5 LU 8BAL +116

Guardians vs. Yankees Injury Updates

Guardians Injuries

  • Shane Bieber
    P

    Bieber is out with elbow

    Out

  • Slade Cecconi
    P

    Cecconi is out with oblique

    Out

  • John Means
    P

    Means is out with elbow

    Out

  • Lane Thomas
    OF

    Thomas is out with wrist

    Out

  • David Fry
    C

    Fry is out with elbow

    Out

Yankees Injuries

  • Gerrit Cole
    P

    Cole is out for season with elbow

    Out for Season

  • DJ LeMahieu
    IF

    LeMahieu is out with calf

    Out

  • Giancarlo Stanton
    DH

    Stanton is out with elbow

    Out

  • Luis Gil
    P

    Gil is out with back

    Out

  • JT Brubaker
    P

    Brubaker is out with ribs

    Out

Yankees vs. Guardians Starting Lineups
Yankees Starting Lineup
Projected
PITCHERW-LERAWHIPK/9
Will Warren logoRW.Warren, P1-05.171.4049.19
HITTERSAVGOBPSLGHR
Ben Rice logo1B.Rice, DH.288.397.5915
Aaron Judge logo2A.Judge, RF.384.490.6987
Cody Bellinger logo3C.Bellinger, CF.183.238.3102
Paul Goldschmidt logo4P.Goldschmidt, 1B.372.421.4651
Jazz Chisholm logo5J.Chisholm, 2B.161.255.4257
Anthony Volpe logo6A.Volpe, SS.217.313.4224
Jasson Dominguez logo7J.Dominguez, LF.232.321.3912
J.C. Escarra logo8J.Escarra, C.158.304.2630
Oswaldo Cabrera logo9O.Cabrera, 3B.302.373.3771
Guardians Starting Lineup
Projected
PITCHERW-LERAWHIPK/9
Tanner Bibee logoRT.Bibee, P1-25.851.5006.75
HITTERSAVGOBPSLGHR
Steven Kwan logo1S.Kwan, LF.333.396.5064
Nolan Jones logo2N.Jones, RF.173.306.2500
Jose Ramirez logo3J.Ramirez, 3B.276.337.5265
Kyle Manzardo logo4K.Manzardo, DH.217.329.5807
Carlos Santana logo5C.Santana, 1B.224.295.3182
Bo Naylor logo6B.Naylor, C.204.298.3472
Angel Martinez logo7A.Martinez, CF.364.353.5150
Daniel Schneemann logo8D.Schneemann, 2B.219.286.4692
Brayan Rocchio logo9B.Rocchio, SS.250.333.2860

Yankees vs. Guardians Odds Comparison

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Yankees at Guardians Team Totals

MatchupOverUnder
Yankees
14-9
N/A
N/A
Guardians
13-9
N/A
N/A