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Bears vs. 49ers Odds & Betting Predictions - December 29, 2025

Bears at 49ers

1:20 am • NBC/Peacock

Chicago Bears

9-4
@

San Francisco 49ers

9-4

Bears at 49ers Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Bears
9-4
N/A
N/A
N/A
49ers
9-4
N/A
N/A
N/A
location pinMonday 1:20 a.m.
December 29, 2025
Levi's StadiumSanta Clara

Bears vs. 49ers Props

Prop Projections

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Prop Odds Comparison

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Line Movement Tracker

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Bears vs. 49ers Public Betting Percentages

Away Logo

Bears

Public

Home Logo

49ers

50%

Bets%

50%

Money%

NFL Public Betting Right Arrow

Betting Trends

  • 49ers are 2-3 in their last 5 games.
  • 49ers are 2-3 in their last 5 games against the spread
  • 49ers are 6-2 in their road games against the spread
  • The totals have gone OVER in 3 of 49ers' last 5 games
  • The totals have gone OVER in 2 of 49ers' 5 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
49ers		8-52-36-26-22-3
Bears		7-5-12-2-15-32-2-15-3

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
49ers		7-62-35-34-43-2
Bears		7-5-12-35-2-13-24-3-1

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
49ers		9-4N/AN/A7-12-3
Bears		9-4N/AN/A4-15-3

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Nov 30th@CLEW 26-8-5.5 WU 35.5SF -250
Nov 25thCARW 20-9-7.5 WU 49SF -375
Nov 16th@ARIW 41-22-3.5 WO 48.5SF -192
Nov 9thLAL 26-42+5.5 LO 49.5LA +212
Nov 2nd@NYGW 34-24-2.5 WO 47.5SF -146

49ers vs. Bears Injury Updates

49ers Injuries

  • Brandon Aiyuk
    WR

    Aiyuk is out with knee

    Out

  • Jacob Cowing
    WR

    Cowing is out with hamstring

    Out

Bears Injuries

  • Rome Odunze
    WR

    Odunze is out with foot

    Out

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Player Stats
  • passing yards
    Mac Jones logo
    Mac Jones
    2151
    pyds
  • passing touchdowns
    Mac Jones logo
    Mac Jones
    13
    ptd
  • rushing yards
    Christian McCaffrey logo
    Christian McCaffrey
    849
    ryds
  • rushing touchdowns
    Christian McCaffrey logo
    Christian McCaffrey
    8
    rtd
Depth Charts
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Starter2ND3RD4TH
QBBrock PurdyMac JonesKurtis Rourke
RBChristian McCaffreyIsaac GuerendoJordan James
WRJauan JenningsJacob CowingSkyy MooreJunior Bergen
TEGeorge KittleLuke FarrellJake TongesBrayden Willis
LTTrent WilliamsSpencer Burford
LGBen BartchNick Zakelj
CJake BrendelMatt HennessyDrake Nugent
RGDominick PuniConnor Colby
RTColton McKivitzAusten Pleasants
LDENick BosaYetur Gross-MatosRobert BealWilliam Bradley-King
RDEMykel WilliamsBryce HuffSam Okuayinonu
WLBDee WintersNick MartinJalen Graham
MLBFred WarnerLuke GiffordTatum BethuneCurtis Robinson
LCBRenardo GreenJakob Robinson
SSJi'Ayir BrownMalik MustaphaDerrick Canteen
FSJason PinnockMarques SigleSiran Neal
RCBDeommodore LenoirDarrell Luter
PThomas Morstead
PRJacob CowingJunior BergenJordan WatkinsRicky Pearsall
KRIsaac GuerendoJunior Bergen
LSJon Weeks
DTKevin GivensAlfred CollinsSebastian ValdezEvan Anderson
FBKyle Juszczyk
RWRRicky PearsallJordan WatkinsMalik Turner
LWRBrandon AiyukMalik Turner
NTJordan ElliottC.J. WestKalia Davis
NBUpton StoutChase Lucas
Team Stats

Passing

2645
YDS
3154
234/402
Comps/Atts
307/450
6.893
YPA
7.329
18/5
TDs/INTs
22/13
19/126
Sacks/Yards
20/144

Rushing

1846
Rush Yards
1281
374
Attempts
366
4.936
YPC
3.5
15
TDs
11

Turnovers

Fumbles Lost
5
Interceptions
13

Efficiency

24/41 58.54%
Redzone
30/48 62.5%
72/164 0%
3rd Down
81/168 0%
8/18 0%
4th Down
10/17 0%

First Downs

254
Total
282
130
Pass
174
108
Rush
90
16
Penalty
18

Misc

/
Penalties/Yards
/
Possession

Bears vs. 49ers Odds Comparison

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Bears at 49ers Team Totals

MatchupOverUnder
Bears
9-4
N/A
N/A
49ers
9-4
N/A
N/A