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Titans vs. Cardinals Odds & Betting Predictions - October 5, 2025

Titans at Cardinals

8:05 pm • CBS

Tennessee Titans

0-4
@

Arizona Cardinals

2-2

Titans at Cardinals Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Titans
0-4
+5.5
+8.5-109
o41.5-108
+350
Cardinals
2-2
u46.5
-8.5-111
u41.5-112
-455
location pinSunday 8:05 p.m.
October 05, 2025
State Farm StadiumGlendale
thermometer image85°Fahrenheit
rain image0%Rain
wind image3Wind
Titans vs. Cardinals Expert Picks
Jim Sannes
Jim Sannes
Last 30d: 15-52-0 (-12.9u)
Over 41.5-105
1u
Have this total around 45 due to the this game being indoors and both defenses being underwhelming.
Sandy Plashkes
Sandy Plashkes
Last 30d: 69-105-3 (-20.3u)
TEN +10-115
1.15u
I’m sorry, this line is absurd. I can’t stop betting the Titans but I am so out on the Cardinals. Keep it within 10 Cam.
FTN Fantasy
FTN Fantasy
Last 30d: 79-91-1 (-20.0u)
TEN +8.5-110
1u

Titans vs. Cardinals Previews & Analysis

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    Sep 30, 2025 UTC
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Titans vs. Cardinals Props

Prop Projections

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Prop Odds Comparison

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Line Movement Tracker

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Titans vs. Cardinals Public Betting Percentages

Away Logo

Titans

Public

Home Logo

Cardinals

41%

Bets%

59%

Money%

NFL Public Betting Right Arrow

Betting Trends

  • Cardinals are 2-2 in their last 5 games.
  • Cardinals are 2-2 in their last 5 games against the spread
  • Cardinals are 2-0 in their road games against the spread
  • The totals have gone OVER in 1 of Cardinals' last 4 games
  • The totals have gone OVER in 1 of Cardinals' 2 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Cardinals		2-20-22-01-11-1
Titans		1-30-21-1N/A1-3

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Cardinals		1-31-10-21-10-2
Titans		2-22-00-2N/A2-2

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Cardinals		2-2N/AN/A2-00-2
Titans		0-4N/AN/AN/A0-4

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Sep 26thSEAL 20-23+1.5 LU 43.5SEA +102
Sep 21st@SFL 15-16+1.5 WU 44.5SF +105
Sep 14thCARW 27-22-7 LO 45.5ARI -310
Sep 7th@NOW 20-13-5.5 WU 44.5ARI -260
Aug 24thLVW 20-10+3 WU 38.5ARI +140

Titans vs. Cardinals Injury Updates

Titans Injuries

  • Tyjae Spears
    RB

    Spears is questionable with ankle

    Questionable

  • Kevin Winston
    S

    Winston is doubtful with hamstring

    Doubtful

  • Kalel Mullings
    RB

    Mullings is out with ankle

    Out

Cardinals Injuries

  • Zay Jones
    WR

    Jones is questionable with concussion

    Questionable

  • James Conner
    RB

    Conner is out with foot

    Out

  • Will Hernandez
    OL

    Hernandez is out with knee

    Out

  • Owen Pappoe
    LB

    Pappoe is questionable with quad

    Questionable

  • Dante Stills
    DE

    Stills is questionable with heel

    Questionable

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Player Stats
  • passing yards
    Kyler Murray logo
    Kyler Murray
    742
    pyds
  • passing touchdowns
    Kyler Murray logo
    Kyler Murray
    6
    ptd
  • rushing yards
    Trey Benson logo
    Trey Benson
    160
    ryds
  • rushing touchdowns
    James Conner logo
    James Conner
    1
    rtd
Depth Charts
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Starter2ND3RD4TH
QBKyler MurrayJacoby Brissett
RBJames ConnerTrey BensonEmari DemercadoMichael CarterBam Knight
WRGreg DortchZay JonesAndre Baccellia
TETrey McBrideTip ReimanElijah HigginsTravis VokolekJosiah Deguara
LTParis JohnsonKelvin BeachumJake Curhan
LGEvan BrownNick Leverett
CHjalte FroholdtJon Gaines
RGIsaiah AdamsWill HernandezHayden Conner
RTJonah WilliamsChristian JonesJosh FryarJeremiah Byers
LDECalais CampbellWalter NolenL.J. CollierAnthony Goodlow
RDEDarius RobinsonJustin JonesBilal Nichols
WLBAkeem Davis-GaitherOwen Pappoe
MLBMack WilsonCody SimonJ.J. Russell
LCBWill JohnsonElijah Jones
SSJalen ThompsonDadrion Taylor-Demerson
FSBudda BakerJoey BlountKitan Crawford
RCBMax MeltonDenzel BurkeEkow Boye-Doe
PBlake Gillikin
HBlake Gillikin
PRGreg DortchXavier Weaver
KRGreg DortchAndre Baccellia
LSAaron Brewer
LWRMarvin HarrisonSimi FehokoTejhaun Palmer
NBGarrett WilliamsKei'Trel ClarkDarren Hall
KChad Ryland
NTDalvin TomlinsonDante StillsPJ Mustipher
RWRMichael WilsonXavier Weaver
ROLBJosh SweatBJ OjulariXavier Thomas
LOLBBaron BrowningZaven CollinsJordan BurchElliott Brown
Team Stats

Passing

494
YDS
659
64/125
Comps/Atts
87/130
4.912
YPA
5.708
2/2
TDs/INTs
6/3
17/120
Sacks/Yards
13/83

Rushing

348
Rush Yards
423
88
Attempts
94
3.955
YPC
4.5
1
TDs
1

Turnovers

Fumbles Lost
2
Interceptions
3

Efficiency

3/7 42.86%
Redzone
7/13 53.85%
15/54 0%
3rd Down
20/52 0%
2/5 0%
4th Down
4/4 0%

First Downs

56
Total
69
31
Pass
42
20
Rush
19
5
Penalty
8

Misc

/
Penalties/Yards
/
Possession

Titans vs. Cardinals Odds Comparison

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Titans at Cardinals Team Totals

MatchupOverUnder
Titans
0-4
N/A
N/A
Cardinals
2-2
N/A
N/A