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Colts vs. Rams Odds & Betting Predictions - September 28, 2025

Colts at Rams

8:05 pm • FOX

Indianapolis Colts

3-0
@

Los Angeles Rams

2-1

Colts at Rams Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Colts
3-0
+6.5
+3.5-111
o49.5-112
+157
Rams
2-1
u46.5
-3.5-109
u49.5-108
-190
location pinSunday 8:05 p.m.
September 28, 2025
SoFi StadiumInglewood
thermometer image76°Fahrenheit
rain image0%Rain
wind image6Wind
Colts vs. Rams Expert Picks
Derek Carty
Derek Carty
Last 30d: 11-15-0 (-1.9u)
J.Taylor u21.5 Rush Att-130
1.2u
THE BLITZ is forecasting 18.82 rush attempts for Jonathan Taylor compared to 25.22 rush attempts implied by sportsbooks, so I believe there is some value here. If you take the under, you’d be projected to win 77% of the time, resulting in a 42% ROI. Based on a $100 wager, the expected value here would be $50.19. Love THE BLITZ? Get all of Carty’s sports betting projections at EV Analytics: https://evanalytics.com/products/nfl-premium-subscription?ref=zdlkmgz
Kendra Middleton
Kendra Middleton
Last 30d: 7-5-0 (+1.4u)
LA -3.5-108
1u
Brandon Kravitz
Brandon Kravitz
Last 30d: 33-43-0 (-10.8u)
Over 49.5-110
1.1u
Markus Markets
Markus Markets
Last 30d: 21-27-2 (-0.6u)
T.Warren o45.5 Rec Yds-110
1u
Mjaybrod
Mjaybrod
Last 30d: 57-71-2 (-8.5u)
LA -3-112
1u
Sorry bout that loss last week (PX fucks so hard)
Roger Goodell
Roger Goodell
Last 30d: 32-26-1 (+1.8u)
LA -3.5-110
1u
Boomer Betz
Boomer Betz
Last 30d: 123-109-1 (+22.8u)
LA -3.5-109
1u

Colts vs. Rams Previews & Analysis

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    NFL Betting Experts Anytime Touchdown Picks For Week 4! | Action Network Podcast

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    Sep 26, 2025 UTC
  • START Daniel Jones or Drake Maye?! | Week 4 DFS Lineup | Fantasy Flex article feature image

    START Daniel Jones or Drake Maye?! | Week 4 DFS Lineup | Fantasy Flex

    chris.raybon•
    Sep 25, 2025 UTC
  • Pro Bettors REVEAL Their NFL Week 4 Long Shot Parlays! article feature image

    Pro Bettors REVEAL Their NFL Week 4 Long Shot Parlays!

    •
    Sep 25, 2025 UTC
  • Anytime Touchdown Picks For Seahawks vs. Cardinals! article feature image

    Anytime Touchdown Picks For Seahawks vs. Cardinals!

    •
    Sep 25, 2025 UTC
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Colts vs. Rams Props

Prop Projections

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Prop Odds Comparison

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Line Movement Tracker

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Colts vs. Rams Public Betting Percentages

Away Logo

Colts

Public

Home Logo

Rams

58%

Bets%

42%

Money%

NFL Public Betting Right Arrow

Betting Trends

  • Rams are 2-1 in their last 5 games.
  • Rams are 2-1 in their last 5 games against the spread
  • Rams are 1-1 in their road games against the spread
  • The totals have gone OVER in 2 of Rams' last 3 games
  • The totals have gone OVER in 0 of Rams' 1 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Rams		2-11-01-12-00-1
Colts		3-02-01-02-01-0

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Rams		2-10-12-01-11-0
Colts		2-11-11-01-11-0

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Rams		2-1N/AN/A2-00-1
Colts		3-0N/AN/A2-01-0

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Sep 21st@PHIL 26-33+3.5 LO 45.5PHI +170
Sep 14th@TENW 33-19-5.5 WO 41.5LA -250
Sep 7thHOUW 14-9-3 WU 43LA -168
Aug 23rd@CLEL 17-19+10 WU 37CLE +360
Aug 16thLACW 23-22+8 WO 39.5LA +297

Rams vs. Colts Injury Updates

Rams Injuries

    Colts Injuries

    • Alec Pierce
      WR

      Pierce is doubtful with concussion

      Doubtful

    See more NFL Injuries Right Arrow
    Player Stats
    • passing yards
      Matthew Stafford logo
      Matthew Stafford
      739
      pyds
    • passing touchdowns
      Matthew Stafford logo
      Matthew Stafford
      5
      ptd
    • rushing yards
      Kyren Williams logo
      Kyren Williams
      226
      ryds
    • rushing touchdowns
      Kyren Williams logo
      Kyren Williams
      1
      rtd
    Depth Charts
    Right Arrow
    Starter2ND3RD4TH
    QBMatthew StaffordJimmy GaroppoloStetson Bennett
    RBKyren WilliamsBlake CorumJarquez HunterRonnie Rivers
    WRTutu AtwellXavier Smith
    TETyler HigbeeColby ParkinsonTerrance FergusonDavis AllenMark Redman
    LTAlaric JacksonD.J. HumphriesAJ Arcuri
    LGSteve AvilaWyatt Bowles
    CColeman SheltonBeaux LimmerDylan McMahon
    RGKevin DotsonJustin Dedich
    RTRob HavensteinWarren McClendonDavid Quessenberry
    RDEBraden FiskeLarrell MurchisonDesjuan Johnson
    LCBDarious WilliamsEmmanuel ForbesA.J. GreenCam Lampkin
    SSKam CurlJaylen McCollough
    FSKamren KinchensTanner IngleNate Valcarcel
    RCBAhkello WitherspoonCobie Durant
    PEthan Evans
    HEthan Evans
    PRXavier Smith
    KRJordan WhittingtonBlake Corum
    LSAlex Ward
    LWRDavante AdamsJordan WhittingtonTru Edwards
    RWRPuka NacuaKonata MumpfieldBrennan Presley
    NBQuentin LakeJosh Wallace
    ROLBJared VerseJosaiah StewartNick Hampton
    LOLBByron YoungJamil Muhammad
    LILBNate LandmanTroy ReederShaun Dolac
    KJoshua Karty
    RILBOmar SpeightsElias Neal
    NTPoona FordTy HamiltonBill Norton
    DTKobie TurnerTyler DavisJack Heflin
    Team Stats

    Passing

    796
    YDS
    710
    63/88
    Comps/Atts
    63/96
    9.273
    YPA
    7.698
    3/0
    TDs/INTs
    5/2
    2/20
    Sacks/Yards
    5/29

    Rushing

    460
    Rush Yards
    381
    100
    Attempts
    81
    4.6
    YPC
    4.704
    6
    TDs
    3

    Turnovers

    Fumbles Lost
    0
    Interceptions
    2

    Efficiency

    7/16 43.75%
    Redzone
    6/13 46.15%
    15/36 0%
    3rd Down
    15/35 0%
    5/7 0%
    4th Down
    2/3 0%

    First Downs

    75
    Total
    62
    40
    Pass
    35
    26
    Rush
    22
    9
    Penalty
    5

    Misc

    /
    Penalties/Yards
    /
    Possession

    Colts vs. Rams Odds Comparison

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    Colts at Rams Team Totals

    MatchupOverUnder
    Colts
    3-0
    N/A
    N/A
    Rams
    2-1
    N/A
    N/A