Rams vs. Eagles Odds & Betting Predictions - September 21, 2025

Projection: -7. Eagles fully healthy with large HFA. For more, check out the Fantasy Life game model.

Puka Nacua ⬆️ 78.5 Receiving Yards (-117 @ BetRiver)(LAR) Nacua has been excellent so far this season. In his first two games he's had 130 and 91 yards in positive game scripts. He's 4th in the league in target rate amongst wide receivers. Crazy enough, Adams is 5th! What this means is LAR is all Puka and Adams with no one else getting looks. Philly plays zone at the 10th highest rate this season (75.3%). Within zone, they play a ton of Cover 3 (32.9%). Puka does very well against Cover 3. Here are last years total stats vs how he did against Cover 3: 2024: 28.3% target share, 76% catch rate, 36.8% team yardage rate, 9.52 yards per target, 12.53 yards per reception and a 34.8% 1st read rate 2024 vs Cover 3: 33.6% target share, 84.6% catch rate, 43.1% team yardage rate, 10.95 yards per target, 12.94 yards per reception and 39.7 1st read rate He was awesome against Cover 3 and he lead the league in target share vs Cover 3! If you are looking for a weak part of this PHI defense it's in the secondary. In the last two against this PHI team Puka has been great: 1/19/25: 6 catches on 14 targets for 97 yards 11/24/24: 9 catches on 13 targets for 117 yards This looks like a great spot for Puka to shove again as this Rams team looks to get revenge from last postseason.

Shootout wild west style

SPICY 🌶️

Projection: 0.47 TDs, +149. For more, check out the Fantasy Life player projections.

We’ve probably hit the floor in this market after Hurts opened with just 23 and 22 attempts. The Eagles are still run-heavy with a -3.4% PROE, but that’s nearly half of last year’s -6.1% rate. His scramble rate is inflated by the 9 on opening night (only 1 last week), so some regression there alone should add 1–2 more attempts. He’s also throwing away 9% of his passes (3rd highest rate) which is actually a positive here, since incompletions pad attempts. He’s averaging a career-low 5.6 aDOT with a 76% completion rate, so more incompletions are coming if/when he starts pushing it downfield more. That could be the case here considering the Rams’ tendency to play single-high should also lead to more downfield shots. Eagles have been pass heavy on 2nd and long so a downfield pass falling incomplete on those would be best case scenario leading to another pass on 3rd (if he doesn’t sack or scramble. We should see more of those types of opps here. There’s even a quirky angle with the NFL cracking down on the tush push; if they turn a 3rd-and-inches into a 3rd-and-5 on a penalty, that’s another spot where Hurts could be forced to throw. Eagles are also “only” 3.5 point favorites which opens the door for a potential rare trailing game script if Rams can get up early, which would lead to more dropbacks for Hurts. This isn’t a massive edge, but stacking all these micro factors nudges his projection up to 27.8 attempts (~58% to clear 26.5). It’s one of those fun “process bets” where small details add up to some “buy low” value.

I remain incredibly skeptical of OC Kevin Patullo's Eagles offense and lean Rams on the number, but I do not like this matchup for LA. The Rams' defense is improving rapidly against the pass, but that's in large part because of a defensive front loaded with small, speedy guys that do a great job getting after the quarterback. That's great in some matchups, but that same front got absolutely dominated in two games against the ginormous Philadelphia line last season, which overpowered the Rams and cruised on the ground. Saquon Barkley ran for an incredible 460 yards in two games against the Rams last season — one in the regular season and one in the playoffs. Barkley ran 26 times for 255 yards and a pair of scores in an easy 37-20 win in the regular season, breaking loose for runs of 70 and 72 yards. Then, when everyone knew how badly that game had gone for this run defense and game planned accordingly, Saquon basically matched the feat in the playoffs: 26 runs for 205 yards and two scores with 62- and 78-yard runs. LA's run defense has been average so far, but that's against the weak rushing attacks and poor lines of the Titans and Texans. This is a different challenge all together, and the Rams have shown no ability to stop this rushing attack. I'm not confident in Eagles, but if Philadelphia does play well, it'll likely be because Saquon Barkley had yet another monster game with his offensive line ripping huge holes through the heart of this defense. I'm not looking for median Barkley outcomes for yardage. We want volume and a chance for him to rip off a long run or two. So let's play that! I'll skip the over 18.5 rushing attempts and play 20+ attempts at +125 (bet365) as the first level of the escalator, then 25+ attempts at +550. If Barkley does get that many touches, maybe he rips off another 60- or 70-yarder. Let's play 150+ yards at +850 and longest rush 50+ yards at +1400 (both bet365), and maybe even a little touch on 200+ yards at +4400 (DraftKings). Those are absurd, irresponsible bets in most settings — but Barkley hit every one of those lines both Rams games last year! Third time's the charm?

@wheatonbrando https://myaction.app/mwsC0lYENWb

Batman with a way bigger dick

FD

@sundaysixpack @Stuckey2 https://myaction.app/4MflgQZkKWb

@Stuckey2 3 https://myaction.app/4MflgQZkKWb

Plant Your Flag Early Pick @Stuckey2 https://myaction.app/4C2HYTivIWb

PHI 4.3 Y/P on offense down 1.3 from ‘24, 5.3 Y/P allowed up 0.6. Inferior version of LAR came 13 yards from beating superior version of PHI in Jan.