Commanders vs. Packers Odds & Betting Predictions - September 12, 2025

👀 Week 2 Lookahead 👀 Each week in this column, I'll play at least one look-ahead line. While everyone else is focused on games this weekend, I'm already looking ahead at next weekend's slate. The goal of the Lookahead is to get ahead of this weekend's results and grab a line now that won't be there next week. This first pick for Week 2 should come as no surprise if you've been following my season previews or even the picks in this column. I like Green Bay a ton this year and expect them to take care of the Lions, which would certainly boost the Packers' profile. I'm also down on Washington with little real strength outside of Jayden Daniels and expect them to struggle with the Giants, maybe even lose. If those results go that direction, there's no chance this stays below the key number of three a week from now. It probably ends up on the other side — and it should. These teams are not in the same class. I slotted the Packers third in my initial power ranking, while the Commanders are closer to the bottom 10. This is effectively the same line Green Bay is getting at home in Week 1 against the Lions — but why in the world would we power rank Washington equal to Detroit? That Lions line dropped a bit because of the Micah Parsons trade, but this one hasn't budged. It should've — Parsons sacked Jayden Daniels 4.5 times in two games last year, and now Washington will have a short week and just one game of film to prepare for how Parsons will be unleashed in this defense. That short week is also an even bigger advantage for Matt LaFleur against Dan Quinn, and LaFleur is outstanding early in the season at 12-3 ATS the first three games, entering this weekend. I don't expect this line to stay below three long, and it's already there at some books. Grab Packers -2.5 while it's still there and we're already set for Thursday night.