Browns vs. Lions Odds & Betting Predictions - September 28, 2025

Browns at Lions

5:00 pm • FOX
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Browns at Lions Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Browns
1-2
+10.5
+9.5-110
o44.5-105
+400
Lions
2-1
u45.5
-9.5-110
u44.5-115
-535
location pinSunday 5:00 p.m.
September 28, 2025
Ford FieldDetroit
Browns vs. Lions Expert Picks
💰🦡 Jake
💰🦡 Jake
Last 30d: 95-108-7 (+34.5u)
DET -8.5-115
1.15u
Jim Sannes
Jim Sannes
Last 30d: 13-36-0 (-2.0u)
DET -8.5-110
1u
Skeptical that the Browns' pass defense can be as good as it has been as they move on the road.
Over 45.5-115
1u
Full respect to the Browns, but think their defense is being overrated in the market coming off a nice showing last week.
Brandon Kravitz
Brandon Kravitz
Last 30d: 33-44-0 (-11.2u)
DET -8.5-110
1.1u
FTN Fantasy
FTN Fantasy
Last 30d: 70-91-0 (-28.9u)
CLE +8.5-110
1u

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Browns vs. Lions Props

Prop Projections

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Prop Odds Comparison

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Line Movement Tracker

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Browns vs. Lions Public Betting Percentages

Away Logo

Browns

Public

46%

Bets%

54%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Lions
2-11-01-11-01-1
Browns
2-12-00-1N/A2-1

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Lions
2-11-01-11-01-1
Browns
1-20-21-0N/A1-2

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Lions
2-1N/AN/A1-01-1
Browns
1-2N/AN/AN/A1-2

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Sep 23rd@BALW 38-30+4.5 WO 53.5DET +195
Sep 14thCHIW 52-21-6.5 WO 46.5DET -295
Sep 7th@GBL 13-27+1.5 LU 48GB -105
Aug 23rdHOUL 7-26+1 LU 34.5HOU +100
Aug 16thMIAL 17-24+0.5 LO 37MIA -114

Browns vs. Lions Injury Updates

Browns Injuries

  • Mike Hall
    DT

    Hall is out with knee

    Out

Lions Injuries

  • Jamarco Jones
    T

    Jones is out with ankle

    Out

  • Shane Zylstra
    TE

    Zylstra is out with ankle

    Out

  • Trevor Nowaske
    LB

    Nowaske is out with elbow

    Out

  • Sione Vaki
    RB

    Vaki is out with hamstring

    Out

Player Stats
  • passing yards
    Jared Goff logo
    Jared Goff
    761
    pyds
  • passing touchdowns
    Jared Goff logo
    Jared Goff
    7
    ptd
  • rushing yards
    David Montgomery logo
    David Montgomery
    233
    ryds
  • rushing touchdowns
    David Montgomery logo
    David Montgomery
    3
    rtd
Depth Charts
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Starter2ND3RD4TH
QBJared GoffKyle Allen
RBJahmyr GibbsDavid MontgomeryCraig ReynoldsSione VakiJacob Saylors
WRAmon-Ra St. BrownDominic LovettJackson Meeks
TESam LaPortaBrock WrightShane ZylstraZach Horton
LTTaylor DeckerGiovanni ManuJamarco Jones
LGChristian MahoganyMiles Frazier
CGraham GlasgowKingsley EguakunTrystan Colon
RGTate RatledgeKayode AwosikaMichael Niese
RTPenei SewellDan SkipperMason Miller
LDEAidan HutchinsonAl-Quadin Muhammad
RDEMarcus DavenportJosh Paschal
WLBAlex AnzaloneMalcolm RodriguezGrant StuardEzekiel Turner
MLBJack CampbellZach Cunningham
LCBTerrion ArnoldKhalil Dorsey
SSBrian Branch
FSKerby JosephRock Ya-SinLoren Strickland
RCBD.J. Reed
PJack Fox
HJack Fox
PRKalif RaymondAmon-Ra St. BrownSione VakiTom KennedyDominic Lovett
KRKalif RaymondCraig ReynoldsSione VakiDominic Lovett
LSHogan Hatten
RWRJameson WilliamsKalif Raymond
DTAlim McNeillTyleik WilliamsMekhi WingoKeith CooperMyles Adams
NBAmik RobertsonAvonte MaddoxErick Hallett
KJake Bates
NTDJ ReaderRoy LopezPat O'ConnorChris Smith
ROLBDerrick BarnesTrevor Nowaske
LWRIsaac TeSlaaTom KennedyRonnie Bell
Team Stats
610
YDS
736
80/129
Comps/Atts
74/95
5.039
YPA
8.011
3/4
TDs/INTs
7/1
6/40
Sacks/Yards
4/25
260
Rush Yards
447
65
Attempts
90
4
YPC
4.967
2
TDs
6

Turnovers

Fumbles Lost
4
Interceptions
1

Efficiency

5/7 71.43%
Redzone
11/16 68.75%
20/47 0%
3rd Down
16/39 0%
4/8 0%
4th Down
7/8 0%

First Downs

54
Total
65
30
Pass
39
17
Rush
24
7
Penalty
2
/
Penalties/Yards
/
Possession

Browns vs. Lions Odds Comparison

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Browns at Lions Team Totals

MatchupOverUnder
Browns
1-2
N/A
N/A
Lions
2-1
N/A
N/A